Description
Antibody Name: | ascl1a Antibody (PACO52690) |
Antibody SKU: | PACO52690 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Zebrafish |
Immunogen: | Recombinant Zebrafish Achaete-scute homolog 1a protein (1-196AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Transcriptional regulator. May mediate transcription activation by binding to the E box-containing promoter (By similarity). Involved in neurogenesis. Required for the development of neurons in the epiphysis, acting partially redundantly with neurog1 and downstream of flh. Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression. Also involved in pituitary development; required cell-autonomously in adenohypophyseal cells for endocrine differentiation and for survival of a subset of cells. |
Synonyms: | Achaete-scute homolog 1a (Zash-1a) (Pituitary-absent protein), ascl1a, ash ash1a asha pia |
UniProt Protein Function: | Transcriptional regulator. May mediate transcription activation by binding to the E box-containing promoter (). Involved in neurogenesis. Required for the development of neurons in the epiphysis, acting partially redundantly with neurog1 and downstream of flh. Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression. Also involved in pituitary development; required cell-autonomously in adenohypophyseal cells for endocrine differentiation and for survival of a subset of cells. |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q90259 |
NCBI GenInfo Identifier: | 20373131 |
NCBI Gene ID: | 30466 |
NCBI Accession: | NP_571294.1 |
UniProt Secondary Accession: | Q90259 |
UniProt Related Accession: | Q90259 |
Molecular Weight: | 21,928 Da |
NCBI Full Name: | achaete-scute homolog 1a |
NCBI Synonym Full Names: | achaete-scute family bHLH transcription factor 1a |
NCBI Official Symbol: | ascl1a |
NCBI Official Synonym Symbols: | ash; asha; zasha; zash1a; Zash-1a; id:ibd5085; im:7138587; si:dkey-264k15.2 |
NCBI Protein Information: | achaete-scute homolog 1a |
UniProt Protein Name: | Achaete-scute homolog 1a |
UniProt Synonym Protein Names: | Pituitary-absent protein |
Protein Family: | Achaete-scute |
UniProt Gene Name: | ascl1a |
UniProt Entry Name: | ASL1A_DANRE |