ASC/TMS1 Polyclonal Antibody
- SKU:
- CAB22555
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | ASC/TMS1 Polyclonal Antibody |
| Product Code: | CAB22555 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HL-60, THP-1, Jurkat(negative), Mouse spleen, Rat spleen, Rat lung |
| Cellular Location: | AIM2 inflammasome complex, cytoplasm, cytosol, endoplasmic reticulum, extracellular region, IkappaB kinase complex, inflammasome complex, mitochondrion, NLRP1 inflammasome complex, NLRP3 inflammasome complex, NLRP6 inflammasome complex, nucleolus, nucleoplasm, nucleus |
Enables identical protein binding activity and protein dimerization activity. Involved in several processes, including activation of cysteine-type endopeptidase activity; positive regulation of cytokine production; and regulation of defense response. Acts upstream of or within several processes, including defense response to Gram-positive bacterium; positive regulation of macromolecule metabolic process; and regulation of autophagy. Located in cytosol; extracellular region; and nucleus. Part of inflammasome complex. Is expressed in several structures, including alimentary system; brain; heart; hemolymphoid system gland; and urinary system. Orthologous to human PYCARD (PYD and CARD domain containing).
| Immunogen: | Recombinant protein of Mouse ASC/TMS1. |
| Sequence: | Email for sequence |
| Synonyms: | Asc, TNS1, masc, CARD5, TMS-1, 9130417A21Rik |
| Calculated MW: | 21kDa |
| Observed MW: | 25kDa |
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