ASB9 Antibody (PACO39814)
- SKU:
- PACO39814
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ASB9 Antibody (PACO39814) |
| Antibody SKU: | PACO39814 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Ankyrin repeat and SOCS box protein 9 protein (1-294AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A. |
| Synonyms: | Ankyrin repeat and SOCS box protein 9 (ASB-9), ASB9 |
| UniProt Protein Function: | ASB9: Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: Xp22.2 Molecular Function:protein binding Biological Process: positive regulation of protein catabolic process; protein ubiquitination |
| NCBI Summary: | This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
| UniProt Code: | Q96DX5 |
| NCBI GenInfo Identifier: | 29839756 |
| NCBI Gene ID: | 140462 |
| NCBI Accession: | Q96DX5.1 |
| UniProt Secondary Accession: | Q96DX5,Q9BVF5, Q9NWS5, Q9Y4T3, A8K8A5, |
| UniProt Related Accession: | Q96DX5 |
| Molecular Weight: | 26,849 Da |
| NCBI Full Name: | Ankyrin repeat and SOCS box protein 9 |
| NCBI Synonym Full Names: | ankyrin repeat and SOCS box containing 9 |
| NCBI Official Symbol: | ASB9 |
| NCBI Protein Information: | ankyrin repeat and SOCS box protein 9 |
| UniProt Protein Name: | Ankyrin repeat and SOCS box protein 9 |
| Protein Family: | Ankyrin repeat and SOCS box protein |
| UniProt Gene Name: | ASB9 |
| UniProt Entry Name: | ASB9_HUMAN |
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