Description
| Antibody Name: | ASB9 Antibody (PACO07876) |
| Antibody SKU: | PACO07876 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Human ASB9 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ankyrin repeat and SOCS box-containing 9;ASB9;DKFZp564L0862;FLJ20636;MGC4954 ; |
| UniProt Protein Function: | ASB9: Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: Xp22.2 Molecular Function:protein binding Biological Process: positive regulation of protein catabolic process; protein ubiquitination |
| NCBI Summary: | This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
| UniProt Code: | Q96DX5 |
| NCBI GenInfo Identifier: | 29839756 |
| NCBI Gene ID: | 140462 |
| NCBI Accession: | Q96DX5.1 |
| UniProt Secondary Accession: | Q96DX5,Q9BVF5, Q9NWS5, Q9Y4T3, A8K8A5, |
| UniProt Related Accession: | Q96DX5 |
| Molecular Weight: | 26,849 Da |
| NCBI Full Name: | Ankyrin repeat and SOCS box protein 9 |
| NCBI Synonym Full Names: | ankyrin repeat and SOCS box containing 9 |
| NCBI Official Symbol: | ASB9 |
| NCBI Protein Information: | ankyrin repeat and SOCS box protein 9 |
| UniProt Protein Name: | Ankyrin repeat and SOCS box protein 9 |
| Protein Family: | Ankyrin repeat and SOCS box protein |
| UniProt Gene Name: | ASB9 |
| UniProt Entry Name: | ASB9_HUMAN |