Name: ASB8 Antibody (PACO40590)
SKU: PACO40590
Availability: OutOfStock

Antibody Name:	ASB8 Antibody (PACO40590)
Antibody SKU:	PACO40590
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200
Species Reactivity:	Human
Immunogen:	Recombinant Human Ankyrin repeat and SOCS box protein 8 protein (12-288AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	Antigen Affinity Purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western blot. All lanes: ASB8 antibody at 1µg/ml + Human placenta tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 32 kDa. Observed band size: 32 kDa.
	Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO40590 at dilution of 1:100.
	Immunohistochemistry of paraffin-embedded human colon cancer using PACO40590 at dilution of 1:100.

Background:	May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Synonyms:	Ankyrin repeat and SOCS box protein 8 (ASB-8), ASB8

UniProt Protein Function:	ASB8: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.Chromosomal Location of Human Ortholog: 12q13.11Cellular Component: cytoplasmBiological Process: protein ubiquitination
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q9H765
NCBI GenInfo Identifier:	13129098
NCBI Gene ID:	140461
NCBI Accession:	NP_077000
UniProt Secondary Accession:	Q9H765,Q547Q2, A8K1P2
UniProt Related Accession:	Q9H765
Molecular Weight:	34.0 kDa (311aa) confirmed by MALDI-TOF
NCBI Full Name:	ankyrin repeat and SOCS box protein 8 isoform a
NCBI Synonym Full Names:	ankyrin repeat and SOCS box containing 8
NCBI Official Symbol:	ASB8
NCBI Official Synonym Symbols:	PP14212
NCBI Protein Information:	ankyrin repeat and SOCS box protein 8
UniProt Protein Name:	Ankyrin repeat and SOCS box protein 8
UniProt Synonym Protein Names:
Protein Family:	Ankyrin repeat and SOCS box protein
UniProt Gene Name:	ASB8
UniProt Entry Name:	ASB8_HUMAN