ASB6 Antibody (PACO40894)
- SKU:
- PACO40894
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ASB6 Antibody (PACO40894) |
| Antibody SKU: | PACO40894 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Ankyrin repeat and SOCS box protein 6 protein (1-197AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO40894 at dilution of 1:100. |
| Background: | Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| Synonyms: | Ankyrin repeat and SOCS box protein 6 (ASB-6), ASB6 |
| UniProt Protein Function: | Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011] |
| UniProt Code: | Q9NWX5 |
| NCBI GenInfo Identifier: | 320202962 |
| NCBI Gene ID: | 140459 |
| NCBI Accession: | NP_001189332.1 |
| UniProt Secondary Accession: | Q9NWX5,Q5SZB7, Q9BV15 |
| UniProt Related Accession: | Q9NWX5 |
| Molecular Weight: | 47 kDa |
| NCBI Full Name: | ankyrin repeat and SOCS box protein 6 isoform 3 |
| NCBI Synonym Full Names: | ankyrin repeat and SOCS box containing 6 |
| NCBI Official Symbol: | ASB6 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | ankyrin repeat and SOCS box protein 6 |
| UniProt Protein Name: | Ankyrin repeat and SOCS box protein 6 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ankyrin repeat and SOCS box protein |
| UniProt Gene Name: | ASB6 |
| UniProt Entry Name: |
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