ASB10 Antibody (PACO15830)
- SKU:
- PACO15830
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ASB10 Antibody (PACO15830) |
| Antibody SKU: | PACO15830 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human ASB10 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: A431 cells, Primary antibody: PACO15830(ASB10 Antibody) at dilution 1/1650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
| Background: | The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene. |
| Synonyms: | ankyrin repeat and SOCS box containing 10 |
| UniProt Protein Function: | ASB10: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 7q36.1Cellular Component: cytoplasm; nucleusDisease: Glaucoma 1, Open Angle, F |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2008] |
| UniProt Code: | Q8WXI3 |
| NCBI GenInfo Identifier: | 126302522 |
| NCBI Gene ID: | 136371 |
| NCBI Accession: | Q8WXI3.2 |
| UniProt Secondary Accession: | Q8WXI3,Q6ZUL6, A0AVH0 |
| UniProt Related Accession: | Q8WXI3 |
| Molecular Weight: | 49,565 Da |
| NCBI Full Name: | Ankyrin repeat and SOCS box protein 10 |
| NCBI Synonym Full Names: | ankyrin repeat and SOCS box containing 10 |
| NCBI Official Symbol: | ASB10 |
| NCBI Official Synonym Symbols: | GLC1F |
| NCBI Protein Information: | ankyrin repeat and SOCS box protein 10 |
| UniProt Protein Name: | Ankyrin repeat and SOCS box protein 10 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ankyrin repeat and SOCS box protein |
| UniProt Gene Name: | ASB10 |
| UniProt Entry Name: | ASB10_HUMAN |
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