ARSI Antibody (PACO00430)
- SKU:
- PACO00430
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- NHP - Monkey
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ARSI Antibody |
| Antibody SKU: | PACO00430 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Monkey |
| Immunogen: | synthesized peptide derived from the Internal region of human Arylsulfatase I. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ARSI; Arylsulfatase I; ASI |
| UniProt Protein Function: | ARSI: Displays arylsulfatase activity at neutral pH, when co- expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts. Belongs to the sulfatase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted, signal peptide; Hydrolase; Secreted; Calcium-binding; EC 3.1.6.-Chromosomal Location of Human Ortholog: 5q32Cellular Component: endoplasmic reticulum lumen; extracellular regionMolecular Function: arylsulfatase activity; metal ion binding; protein bindingBiological Process: cellular protein metabolic process; glycosphingolipid metabolic process; post-translational protein modification; sphingolipid metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | Sulfatases (EC 3.1.5.6), such as ARSI, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q5FYB1 |
| NCBI GenInfo Identifier: | 74722581 |
| NCBI Gene ID: | 340075 |
| NCBI Accession: | Q5FYB1.1 |
| UniProt Secondary Accession: | Q5FYB1,A1L3B0, B3KV22, B7XD03 |
| UniProt Related Accession: | Q5FYB1 |
| Molecular Weight: | 48,253 Da |
| NCBI Full Name: | Arylsulfatase I |
| NCBI Synonym Full Names: | arylsulfatase family member I |
| NCBI Official Symbol: | ARSI |
| NCBI Official Synonym Symbols: | SPG66 |
| NCBI Protein Information: | arylsulfatase I |
| UniProt Protein Name: | Arylsulfatase I |
| UniProt Synonym Protein Names: | |
| Protein Family: | Arylsulfatase |
| UniProt Gene Name: | ARSI |
| UniProt Entry Name: | ARSI_HUMAN |
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