Antibody Name:	ARPC4 Antibody (PACO18584)
Antibody SKU:	PACO18584
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide of human ARPC4

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO18584(ARPC4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200).
	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18584(ARPC4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein.

Synonyms:

actin related protein 2/3 complex, subunit 4, 20kDa

UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:	This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010]
UniProt Code:	P59998
NCBI GenInfo Identifier:	311771642
NCBI Gene ID:	10093
NCBI Accession:	NM_005718.4
UniProt Secondary Accession:	P59998
UniProt Related Accession:	P59998
Molecular Weight:
NCBI Full Name:	Homo sapiens actin related protein 2/3 complex subunit 4 (ARPC4), transcript variant 1, mRNA
NCBI Synonym Full Names:	actin related protein 2/3 complex subunit 4
NCBI Official Symbol:	ARPC4
NCBI Official Synonym Symbols:	ARC20; P20-ARC
NCBI Protein Information:	actin-related protein 2/3 complex subunit 4
UniProt Protein Name:	Actin-related protein 2/3 complex subunit 4
UniProt Synonym Protein Names:	Arp2/3 complex 20 kDa subunit
Protein Family:	Actin-related protein 2/3 complex
UniProt Gene Name:	ARPC4
UniProt Entry Name:	ARPC4_HUMAN