ARL8A Antibody (PACO15526)
- SKU:
- PACO15526
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ARL8A Antibody (PACO15526) |
| Antibody SKU: | PACO15526 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human ARL8A |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO15526(ARL8A Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15526(ARL8A Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | ARL8A (ADP-ribosylation factor-like protein 8A), also known as ARL10B or GIE2, is a 186 amino acid, protein that localizes to the membrane of late endosomes. Expressed ubiquitously, ARL8A is thought to play a role in lysosomal motility and may also be involved in chromosomal segregation events. The gene encoding ARL8A maps to human chromosome 1, which spans 260 million base pairs, houses over 3,000 genes and comprises nearly 8% of the human genome. |
| Synonyms: | ADP-ribosylation factor-like 8A |
| UniProt Protein Function: | ARL8A: May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation. Belongs to the small GTPase superfamily. Arf family.Protein type: G protein, monomeric; G protein, monomeric, ARFChromosomal Location of Human Ortholog: 1q32.1Cellular Component: cytoplasm; lysosomal membrane; membrane; midbody; spindle midzoneMolecular Function: alpha-tubulin binding; beta-tubulin binding; GTP binding; protein bindingBiological Process: chromosome segregation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96BM9 |
| NCBI GenInfo Identifier: | 74751775 |
| NCBI Gene ID: | 127829 |
| NCBI Accession: | Q96BM9.1 |
| UniProt Secondary Accession: | Q96BM9,B3KXD0 |
| UniProt Related Accession: | Q96BM9 |
| Molecular Weight: | 21,416 Da |
| NCBI Full Name: | ADP-ribosylation factor-like protein 8A |
| NCBI Synonym Full Names: | ADP ribosylation factor like GTPase 8A |
| NCBI Official Symbol: | ARL8A |
| NCBI Official Synonym Symbols: | GIE2; ARL10B |
| NCBI Protein Information: | ADP-ribosylation factor-like protein 8A |
| UniProt Protein Name: | ADP-ribosylation factor-like protein 8A |
| UniProt Synonym Protein Names: | ADP-ribosylation factor-like protein 10B; Novel small G protein indispensable for equal chromosome segregation 2 |
| Protein Family: | ADP-ribosylation factor-like protein |
| UniProt Gene Name: | ARL8A |
| UniProt Entry Name: | ARL8A_HUMAN |
| Antibodies |
| ARL8A Antibody (PACO07852) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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