Antibody Name:	ARID4B Antibody
Antibody SKU:	PACO00475
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	WB:1:500-1:2000
Species Reactivity:	Human, Mouse, Rat
Immunogen:	synthesized peptide derived from the Internal region of human BRCAA1.

Form:	Liquid
Storage Buffer:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Synonyms:

ARID4B; BRCAA1; RBBP1L1; RBP1L1; SAP180; AT-rich interactive domain-containing protein 4B; ARID domain-containing protein 4B; 180 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p180; Breast cancer-associated antigen BRCAA1; Hi

UniProt Protein Function:	ARID4B: Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:DNA-binding Chromosomal Location of Human Ortholog: 1q42.3 Cellular Component: nucleoplasm; cytoplasm; nucleus Molecular Function:protein binding Biological Process: regulation of transcription from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; genetic imprinting; transcription, DNA-dependent; negative regulation of gene expression, epigenetic; positive regulation of transcription from RNA polymerase II promoter; gene expression; spermatogenesis; regulation of gene expression, epigenetic
NCBI Summary:	This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
UniProt Code:	Q4LE39
NCBI GenInfo Identifier:	143955276
NCBI Gene ID:	51742
NCBI Accession:	Q4LE39.2
UniProt Secondary Accession:	Q4LE39,Q3MHV4, Q5HY99, Q5T2C2, Q5T2C3, Q5T2C4, Q5T2C5 Q5T2C6, Q6P600, Q86UX1, Q86WR4, A1L465,
UniProt Related Accession:	Q4LE39
Molecular Weight:	91,140 Da
NCBI Full Name:	AT-rich interactive domain-containing protein 4B
NCBI Synonym Full Names:	AT rich interactive domain 4B (RBP1-like)
NCBI Official Symbol:	ARID4B
NCBI Official Synonym Symbols:	BCAA; BRCAA1; RBP1L1; SAP180; RBBP1L1
NCBI Protein Information:	AT-rich interactive domain-containing protein 4B; Rb-binding protein homolog; SIN3A-associated protein 180; sin3-associated polypeptide p180; ARID domain-containing protein 4B; breast cancer-associated antigen 1; 180 kDa Sin3-associated polypeptide; breast carcinoma-associated antigen; breast cancer-associated antigen BRCAA1; retinoblastoma-binding protein 1-like 1; histone deacetylase complex subunit SAP180
UniProt Protein Name:	AT-rich interactive domain-containing protein 4B
UniProt Synonym Protein Names:	180 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p180; Breast cancer-associated antigen BRCAA1; Histone deacetylase complex subunit SAP180; Retinoblastoma-binding protein 1-like 1
Protein Family:	AT-rich interactive domain-containing protein
UniProt Gene Name:	ARID4B
UniProt Entry Name:	ARI4B_HUMAN