Description
| Antibody Name: | ARHGEF19 Antibody (PACO22574) |
| Antibody SKU: | PACO22574 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human ARHGEF19. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using ARHGEF19 antibody. |
| Background: | Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase By similarity. |
| Synonyms: | Rho guanine nucleotide exchange factor 19; ARHGEF19; |
| UniProt Protein Function: | ARHGEF19: Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs, Rac/Rho; GEFsChromosomal Location of Human Ortholog: 1p36.13Molecular Function: protein binding; Rho guanyl-nucleotide exchange factor activity; GTPase activator activityBiological Process: wound healing; regulation of actin cytoskeleton organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA, MIM 165390).[supplied by OMIM, Dec 2008] |
| UniProt Code: | Q8IW93 |
| NCBI GenInfo Identifier: | 40255149 |
| NCBI Gene ID: | 128272 |
| NCBI Accession: | NP_694945.2 |
| UniProt Secondary Accession: | Q8IW93,Q5TEV2, Q6PJQ4, Q8N244, A6NJ04 |
| UniProt Related Accession: | Q8IW93 |
| Molecular Weight: | 55,022 Da |
| NCBI Full Name: | rho guanine nucleotide exchange factor 19 |
| NCBI Synonym Full Names: | Rho guanine nucleotide exchange factor (GEF) 19 |
| NCBI Official Symbol: | ARHGEF19 |
| NCBI Official Synonym Symbols: | WGEF |
| NCBI Protein Information: | rho guanine nucleotide exchange factor 19; ephexin-2; weakly similar to Rho GEF |
| UniProt Protein Name: | Rho guanine nucleotide exchange factor 19 |
| UniProt Synonym Protein Names: | Ephexin-2 |
| Protein Family: | |
| UniProt Gene Name: | ARHGEF19 |
| UniProt Entry Name: | ARHGJ_HUMAN |
| Antibodies |
| ARHGEF19 Antibody (PACO00421) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
