Description
| Antibody Name: | ARHGEF19 Antibody |
| Antibody SKU: | PACO00421 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human ARHGEF19. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ARHGEF19; Rho guanine nucleotide exchange factor 19; Ephexin-2 |
| UniProt Protein Function: | ARHGEF19: Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs, Rac/Rho; GEFsChromosomal Location of Human Ortholog: 1p36.13Molecular Function: protein binding; Rho guanyl-nucleotide exchange factor activity; GTPase activator activityBiological Process: wound healing; regulation of actin cytoskeleton organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA, MIM 165390).[supplied by OMIM, Dec 2008] |
| UniProt Code: | Q8IW93 |
| NCBI GenInfo Identifier: | 40255149 |
| NCBI Gene ID: | 128272 |
| NCBI Accession: | NP_694945.2 |
| UniProt Secondary Accession: | Q8IW93,Q5TEV2, Q6PJQ4, Q8N244, A6NJ04 |
| UniProt Related Accession: | Q8IW93 |
| Molecular Weight: | 55,022 Da |
| NCBI Full Name: | rho guanine nucleotide exchange factor 19 |
| NCBI Synonym Full Names: | Rho guanine nucleotide exchange factor (GEF) 19 |
| NCBI Official Symbol: | ARHGEF19 |
| NCBI Official Synonym Symbols: | WGEF |
| NCBI Protein Information: | rho guanine nucleotide exchange factor 19; ephexin-2; weakly similar to Rho GEF |
| UniProt Protein Name: | Rho guanine nucleotide exchange factor 19 |
| UniProt Synonym Protein Names: | Ephexin-2 |
| Protein Family: | |
| UniProt Gene Name: | ARHGEF19 |
| UniProt Entry Name: | ARHGJ_HUMAN |