ARHGEF16 Antibody (PACO22573)
- SKU:
- PACO22573
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ARHGEF16 Antibody (PACO22573) |
| Antibody SKU: | PACO22573 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from Internal of human ARHGEF16. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from A549 cells, using ARHGEF16 antibody. |
| Background: | Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6. |
| Synonyms: | ARHGEF16; ARHGG; GEF16; NBR; Rho guanine exchange factor (GEF) 16 |
| UniProt Protein Function: | ARHGEF16: a Rho guanine exchange factor protein that contains 1 DH, 1 PH and 1 SH3 domain.Protein type: GEFs; Motility/polarity/chemotaxis; GEFs, Rac/RhoChromosomal Location of Human Ortholog: 1p36.3Cellular Component: cytosolMolecular Function: protein binding; Rho guanyl-nucleotide exchange factor activity; Rho GTPase binding; receptor tyrosine kinase binding; PDZ domain bindingBiological Process: regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q5VV41 |
| NCBI GenInfo Identifier: | 163792208 |
| NCBI Gene ID: | 27237 |
| NCBI Accession: | NP_055263.2 |
| UniProt Secondary Accession: | Q5VV41,Q86TF0, Q99434 |
| UniProt Related Accession: | Q5VV41 |
| Molecular Weight: | 80,105 Da |
| NCBI Full Name: | rho guanine nucleotide exchange factor 16 |
| NCBI Synonym Full Names: | Rho guanine nucleotide exchange factor (GEF) 16 |
| NCBI Official Symbol: | ARHGEF16 |
| NCBI Official Synonym Symbols: | NBR; GEF16 |
| NCBI Protein Information: | rho guanine nucleotide exchange factor 16; ephexin-4; Rho guanine exchange factor (GEF) 16 |
| UniProt Protein Name: | Rho guanine nucleotide exchange factor 16 |
| UniProt Synonym Protein Names: | Ephexin-4 |
| Protein Family: | Rho guanine nucleotide exchange factor |
| UniProt Gene Name: | ARHGEF16 |
| UniProt Entry Name: | ARHGG_HUMAN |
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