ARHGAP42 Antibody (PACO46458)
- SKU:
- PACO46458
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ARHGAP42 Antibody (PACO46458) |
| Antibody SKU: | PACO46458 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Rho GTPase-activating protein 42 protein (541-728AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO46458 at dilution of 1:100. |
 | Western Blot. Positive WB detected in: Human placenta tissue. All lanes: ARHGAP42 antibody at 2.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 99 kDa. Observed band size: 99 kDa. |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO46458 at dilution of 1:100. |
| Background: | May influence blood pressure by functioning as a GTPase-activating protein for RHOA in vascular smooth muscle. |
| Synonyms: | Rho GTPase-activating protein 42 (Rho GTPase-activating protein 10-like) (Rho-type GTPase-activating protein 42), ARHGAP42, GRAF3 |
| UniProt Protein Function: | May influence blood pressure by functioning as a GTPase-activating protein for RHOA in vascular smooth muscle. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017] |
| UniProt Code: | A6NI28 |
| NCBI GenInfo Identifier: | 221307575 |
| NCBI Gene ID: | 143872 |
| NCBI Accession: | NP_689645.2 |
| UniProt Secondary Accession: | A6NI28 |
| UniProt Related Accession: | A6NI28 |
| Molecular Weight: | 99kDa |
| NCBI Full Name: | rho GTPase-activating protein 42 isoform 1 |
| NCBI Synonym Full Names: | Rho GTPase activating protein 42 |
| NCBI Official Symbol: | ARHGAP42 |
| NCBI Official Synonym Symbols: | AD031; GRAF3; TMEM133 |
| NCBI Protein Information: | rho GTPase-activating protein 42 |
| UniProt Protein Name: | Rho GTPase-activating protein 42 |
| UniProt Synonym Protein Names: | Rho GTPase-activating protein 10-like; Rho-type GTPase-activating protein 42 |
| Protein Family: | |
| UniProt Gene Name: | ARHGAP42 |
| UniProt Entry Name: |
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