ARHGAP26 Antibody (PACO43679)
- SKU:
- PACO43679
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ARHGAP26 Antibody (PACO43679) |
| Antibody SKU: | PACO43679 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Rho GTPase-activating protein 26 protein (625-814AA) |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO43679 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO43679 at dilution of 1:100. |
| Background: | GTPase-activating protein for RHOA and CDC42. |
| Synonyms: | Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26), ARHGAP26, GRAF KIAA0621 OPHN1L |
| UniProt Protein Function: | ARHGAP26: GTPase-activating protein for RHOA and CDC42. Interacts with NYAP1, NYAP2 and MYO16. Binds to the C-terminus of PTK2/FAK1. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs; GAPs, Rac/Rho; Oncoprotein; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 5q31Cellular Component: cytosolMolecular Function: GTPase activator activity; phospholipid binding; protein bindingBiological Process: regulation of small GTPase mediated signal transductionDisease: Juvenile Myelomonocytic Leukemia |
| UniProt Protein Details: | |
| NCBI Summary: | Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q9UNA1 |
| NCBI GenInfo Identifier: | 21759332 |
| NCBI Gene ID: | 23092 |
| NCBI Accession: | Q9UNA1.1 |
| UniProt Secondary Accession: | Q9UNA1,O75117, Q5D035, Q9BYS6, Q9BYS7, Q9UJ00 |
| UniProt Related Accession: | Q9UNA1 |
| Molecular Weight: | 86,165 Da |
| NCBI Full Name: | Rho GTPase-activating protein 26 |
| NCBI Synonym Full Names: | Rho GTPase activating protein 26 |
| NCBI Official Symbol: | ARHGAP26 |
| NCBI Official Synonym Symbols: | GRAF; GRAF1; OPHN1L; OPHN1L1 |
| NCBI Protein Information: | rho GTPase-activating protein 26 |
| UniProt Protein Name: | Rho GTPase-activating protein 26 |
| UniProt Synonym Protein Names: | GTPase regulator associated with focal adhesion kinase; Oligophrenin-1-like protein; Rho-type GTPase-activating protein 26 |
| Protein Family: | Rho GTPase-activating protein |
| UniProt Gene Name: | ARHGAP26 |
| UniProt Entry Name: | RHG26_HUMAN |
| Antibodies |
| ARHGAP26 Antibody (PACO07824) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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