ARHGAP19 Antibody (PACO35782)
- SKU:
- PACO35782
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ARHGAP19 Antibody (PACO35782) |
| Antibody SKU: | PACO35782 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Rho GTPase-activating protein 19 protein (1-494AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO35782 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO35782 at dilution of 1:100. |
| Background: | GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. |
| Synonyms: | Rho GTPase-activating protein 19 (Rho-type GTPase-activating protein 19), ARHGAP19 |
| UniProt Protein Function: | ARHGAP19: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. 7 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, Rac/Rho; GAPsChromosomal Location of Human Ortholog: 10q24.1Cellular Component: cytosolMolecular Function: GTPase activator activityBiological Process: regulation of small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | Members of the ARHGAP family, such as ARHGAP19, encode negative regulators of Rho GTPases (see RHOA; MIM 165390), which are involved in cell migration, proliferation, and differentiation, actin remodeling, and G1 cell cycle progression (Lv et al., 2007 [PubMed 17454002]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q14CB8 |
| NCBI GenInfo Identifier: | 121948181 |
| NCBI Gene ID: | 84986 |
| NCBI Accession: | Q14CB8.1 |
| UniProt Secondary Accession: | Q14CB8,Q14CF2, Q5J8M2, Q5T460, Q5T462, Q68DG6, Q8N9X1 Q8NF34, Q8TEK1, A1XCP1 |
| UniProt Related Accession: | Q14CB8 |
| Molecular Weight: | 54,081 Da |
| NCBI Full Name: | Rho GTPase-activating protein 19 |
| NCBI Synonym Full Names: | Rho GTPase activating protein 19 |
| NCBI Official Symbol: | ARHGAP19 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | rho GTPase-activating protein 19 |
| UniProt Protein Name: | Rho GTPase-activating protein 19 |
| UniProt Synonym Protein Names: | Rho-type GTPase-activating protein 19 |
| Protein Family: | Rho GTPase-activating protein |
| UniProt Gene Name: | ARHGAP19 |
| UniProt Entry Name: | RHG19_HUMAN |
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