ARHGAP15 Antibody (PACO15506)
- SKU:
- PACO15506
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ARHGAP15 Antibody (PACO15506) |
| Antibody SKU: | PACO15506 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human ARHGAP15 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15506(ARHGAP15 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Jurkat cells, 293T cells, Primary antibody: PACO15506(ARHGAP15 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15506(ARHGAP15 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | RHO GTPases regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15. GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction. |
| Synonyms: | Rho GTPase activating protein 15 |
| UniProt Protein Function: | ARHGAP15: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction.Protein type: GAPs, Rac/Rho; GAPsChromosomal Location of Human Ortholog: 2q22.2-q22.3Cellular Component: membrane; cytosolBiological Process: regulation of cell shape; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q53QZ3 |
| NCBI GenInfo Identifier: | 28274758 |
| NCBI Gene ID: | 55843 |
| NCBI Accession: | AAO34684.1 |
| UniProt Secondary Accession: | Q53QZ3,Q53R36, Q53RD7, Q53RT6, Q53SX9, Q584N9, Q6PJE6 Q86WP1, Q8IXX1, Q9NRL8 |
| UniProt Related Accession: | Q53QZ3 |
| Molecular Weight: | |
| NCBI Full Name: | ARHGAP15 |
| NCBI Synonym Full Names: | Rho GTPase activating protein 15 |
| NCBI Official Symbol: | ARHGAP15 |
| NCBI Official Synonym Symbols: | BM046 |
| NCBI Protein Information: | rho GTPase-activating protein 15; rho-type GTPase-activating protein 15 |
| UniProt Protein Name: | Rho GTPase-activating protein 15 |
| UniProt Synonym Protein Names: | ArhGAP15; Rho-type GTPase-activating protein 15 |
| Protein Family: | Rho GTPase-activating protein |
| UniProt Gene Name: | ARHGAP15 |
| UniProt Entry Name: | RHG15_HUMAN |
| Antibodies |
| ARHGAP15 Antibody (PACO07819) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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