Description
| Antibody Name: | ARHGAP15 Antibody (PACO07819) |
| Antibody SKU: | PACO07819 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human ARHGAP15 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | Rho GTPase activating protein 15;ARHGAP15;BM046 ; |
| UniProt Protein Function: | ARHGAP15: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction.Protein type: GAPs, Rac/Rho; GAPsChromosomal Location of Human Ortholog: 2q22.2-q22.3Cellular Component: membrane; cytosolBiological Process: regulation of cell shape; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q53QZ3 |
| NCBI GenInfo Identifier: | 28274758 |
| NCBI Gene ID: | 55843 |
| NCBI Accession: | AAO34684.1 |
| UniProt Secondary Accession: | Q53QZ3,Q53R36, Q53RD7, Q53RT6, Q53SX9, Q584N9, Q6PJE6 Q86WP1, Q8IXX1, Q9NRL8 |
| UniProt Related Accession: | Q53QZ3 |
| Molecular Weight: | |
| NCBI Full Name: | ARHGAP15 |
| NCBI Synonym Full Names: | Rho GTPase activating protein 15 |
| NCBI Official Symbol: | ARHGAP15 |
| NCBI Official Synonym Symbols: | BM046 |
| NCBI Protein Information: | rho GTPase-activating protein 15; rho-type GTPase-activating protein 15 |
| UniProt Protein Name: | Rho GTPase-activating protein 15 |
| UniProt Synonym Protein Names: | ArhGAP15; Rho-type GTPase-activating protein 15 |
| Protein Family: | Rho GTPase-activating protein |
| UniProt Gene Name: | ARHGAP15 |
| UniProt Entry Name: | RHG15_HUMAN |