Arginase 1 (ARG1) Monoclonal Antibody
- SKU:
- CAB22410
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | Arginase 1 (ARG1) Monoclonal Antibody |
| Product Code: | CAB22410 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC5014-08 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2 |
| Cellular Location: | Cytoplasm, nuclear |
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-322 of Arginase 1 (ARG1) (NP_000036.2). |
| Sequence: | MSAKS RTIGI IGAPF SKGQP RGGVE EGPTV LRKAG LLEKL KEQEC DVKDY GDLPF ADIPN DSPFQ IVKNP RSVGK ASEQL AGKVA EVKKN GRISL VLGGD HSLAI GSISG HARVH PDLGV IWVDA HTDIN TPLTT TSGNL HGQPV SFLLK ELKGK IPDVP GFSWV TPCIS AKDIV YIGLR DVDPG EHYIL KTLGI KYFSM TEVDR LGIGK VMEET LSYLL GRKKR PIHLS FDVDG LDPSF TPATG TPVVG GLTYR EGLYI TEEIY KTGLL SGLDI MEVNP SLGKT PEEVT RTVNT AVAIT LACFG LAREG NHKPI DYLNP PK |
| Synonyms: | ARG1, arginase-1 |
| Calculated MW: | 35kDa |
| Observed MW: | 40kDa |
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