AQP7 Antibody (PACO20987)
- SKU:
- PACO20987
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AQP7 Antibody (PACO20987) |
| Antibody SKU: | PACO20987 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human AQP7 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20987(AQP7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20987(AQP7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function. |
| Synonyms: | aquaporin 7 |
| UniProt Protein Function: | AQP7: Forms a channel for water and glycerol. Belongs to the MIP/aquaporin (TC 1.A.8) family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, aquaporin familyChromosomal Location of Human Ortholog: 9p13Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; intercellular junctionMolecular Function: urea transmembrane transporter activity; water channel activity; glycerol channel activityBiological Process: glycerol transport; generation of precursor metabolites and energy; cellular water homeostasis; water transport; excretion; transmembrane transportDisease: Glycerol Quantitative Trait Locus |
| UniProt Protein Details: | |
| NCBI Summary: | Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O14520 |
| NCBI GenInfo Identifier: | 3121761 |
| NCBI Gene ID: | 364 |
| NCBI Accession: | O14520.1 |
| UniProt Secondary Accession: | O14520,Q08E94, Q5T5L9, Q8NHM3 |
| UniProt Related Accession: | O14520 |
| Molecular Weight: | 17,954 Da |
| NCBI Full Name: | Aquaporin-7 |
| NCBI Synonym Full Names: | aquaporin 7 |
| NCBI Official Symbol: | AQP7 |
| NCBI Official Synonym Symbols: | AQP9; AQP7L; AQPap; GLYCQTL |
| NCBI Protein Information: | aquaporin-7; AQP-7; aquaporin adipose; aquaglyceroporin-7 |
| UniProt Protein Name: | Aquaporin-7 |
| UniProt Synonym Protein Names: | Aquaglyceroporin-7; Aquaporin adipose; AQPap; Aquaporin-7-like |
| Protein Family: | Aquaporin |
| UniProt Gene Name: | AQP7 |
| UniProt Entry Name: | AQP7_HUMAN |
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