Description
| Product Name: | AQP2 Polyclonal Antibody |
| Product Code: | CAB12998 |
| Reactivity: | Mouse |
| Applications: | Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | IHC-P, ELISA |
| Key Applications: | Immunohistochemistry |
| Recommended Dilution: | IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | Apical cell membrane, Basolateral cell membrane, Cytoplasmic vesicle membrane, Golgi apparatus, Multi-pass membrane protein, trans-Golgi network membrane |
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 147-271 of human AQP2 (NP_000477.1). |
| Sequence: | ASTDE RRGEN PGTPA LSIGF SVALG HLLGI HYTGC SMNPA RSLAP AVVTG KFDDH WVFWI GPLVG AILGS LLYNY VLFPP AKSLS ERLAV LKGLE PDTDW EEREV RRRQS VELHS PQSLP RGTKA |
| Synonyms: | NDI2, AQP-CD, WCH-CD |
| Calculated MW: | 29kDa |
| Observed MW: | Refer to figures |