APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.
Product Name:
Apolipoprotein C-II/APOC2 Recombinant Protein (RPES2867)
Product Code:
RPES2867
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Apolipoprotein C-II, Apolipoprotein C2, APC2 and APOC2
Accession:
P02655
Sequence:
Met 1-Glu82
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Apolipoprotein C-II is produced by our E.coli expression system and the target gene encoding Met1-Glu82 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
10.0 kDa
AP Mol Mass:
14 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mMPB,150mM NaCL,30%glycerol,pH7.2.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.