Apolipoprotein A1/APOA1 Monoclonal Antibody (CAB24290)
- SKU:
- CAB24290
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | Apolipoprotein A1/APOA1 Monoclonal Antibody |
| Product Code: | CAB24290 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63059 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Hep G2, Mouse plasma, Rat plasma |
| Cellular Location: | Blood microparticle, cytoplasmic vesicle, cytosol, early endosome, endoplasmic reticulum lumen, extracellular exosome, extracellular region, extracellular space, extracellular vesicle, plasma membrane |
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-267 of human Apolipoprotein A1/APOA1 (NP_000030.1). |
| Sequence: | DEPPQ SPWDR VKDLA TVYVD VLKDS GRDYV SQFEG SALGK QLNLK LLDNW DSVTS TFSKL REQLG PVTQE FWDNL EKETE GLRQE MSKDL EEVKA KVQPY LDDFQ KKWQE EMELY RQKVE PLRAE LQEGA RQKLH ELQEK LSPLG EEMRD RARAH VDALR THLAP YSDEL RQRLA ARLEA LKENG GARLA EYHAK ATEHL STLSE KAKPA LEDLR QGLLP VLESF KVSFL SALEE YTKKL NTQ |
| Synonyms: | HPALP2, apo(a) |
| Calculated MW: | 28kDa |
| Observed MW: | 28kDa |
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Apolipoprotein A1/APOA1 Monoclonal Antibody (CAB24291)
