APOLD1 Antibody (PACO62591)
- SKU:
- PACO62591
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | APOLD1 Antibody (PACO62591) |
| Antibody SKU: | PACO62591 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Apolipoprotein L domain-containing protein 1 protein (213-274AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of Hela cells with PACO62591 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood-brain permeability. |
| Synonyms: | Apolipoprotein L domain-containing protein 1 (Vascular early response gene protein), APOLD1, VERGE |
| UniProt Protein Function: | APOLD1: May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood- brain permeability. Belongs to the apolipoprotein L family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Lipid-binding; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 12p13.1Cellular Component: plasma membrane; extracellular region; integral to membraneMolecular Function: lipid bindingBiological Process: response to hypoxia; lipoprotein metabolic process; angiogenesis; cell differentiation; lipid transport; regulation of endothelial cell differentiation; endothelial cell activation |
| UniProt Protein Details: | |
| NCBI Summary: | APOLD1 is an endothelial cell early response protein that may play a role in regulation of endothelial cell signaling and vascular function (Regard et al., 2004 [PubMed 15102925]).[supplied by OMIM, Dec 2008] |
| UniProt Code: | Q96LR9 |
| NCBI GenInfo Identifier: | 194353995 |
| NCBI Gene ID: | 81575 |
| NCBI Accession: | NP_001123887.1 |
| UniProt Secondary Accession: | Q96LR9,Q8IVR2, Q9H0I5 |
| UniProt Related Accession: | Q96LR9 |
| Molecular Weight: | 27,063 Da |
| NCBI Full Name: | apolipoprotein L domain-containing protein 1 isoform 1 |
| NCBI Synonym Full Names: | apolipoprotein L domain containing 1 |
| NCBI Official Symbol: | APOLD1 |
| NCBI Official Synonym Symbols: | VERGE |
| NCBI Protein Information: | apolipoprotein L domain-containing protein 1 |
| UniProt Protein Name: | Apolipoprotein L domain-containing protein 1 |
| UniProt Synonym Protein Names: | Vascular early response gene protein |
| Protein Family: | Apolipoprotein |
| UniProt Gene Name: | APOLD1 |
| UniProt Entry Name: | APLD1_HUMAN |
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