Description
Antibody Name: | Apoa4 Antibody (PACO24990) |
Antibody SKU: | PACO24990 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Mouse |
Immunogen: | Recombinant Mouse Apolipoprotein A-IV protein (21-395AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. |
Synonyms: | Apolipoprotein A-IV (Apo-AIV) (ApoA-IV) (Apolipoprotein A4), Apoa4 |
UniProt Protein Function: | APOA4: May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. Synthesized primarily in the intestine and secreted in plasma. Belongs to the apolipoprotein A1/A4/E family.Protein type: Cell adhesion; Endoplasmic reticulum; Lipid-binding; Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 9 A5.2|9 25.36 cMCellular Component: cell surface; chylomicron; extracellular matrix; extracellular region; extracellular spaceMolecular Function: antioxidant activity; cholesterol binding; cholesterol transporter activity; copper ion binding; lipid binding; phosphatidylcholine binding; protein homodimerization activityBiological Process: cholesterol biosynthetic process; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; hydrogen peroxide catabolic process; innate immune response in mucosa; leukocyte adhesion; lipid homeostasis; lipid transport; lipoprotein metabolic process; multicellular organismal lipid catabolic process; neuron projection regeneration; phosphatidylcholine metabolic process; phospholipid efflux; positive regulation of fatty acid biosynthetic process; positive regulation of lipoprotein lipase activity; protein-lipid complex assembly; regulation of cholesterol transport; regulation of intestinal cholesterol absorption; removal of superoxide radicals; response to lipid hydroperoxide; reverse cholesterol transport; transport; triglyceride catabolic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P06728 |
NCBI GenInfo Identifier: | 110347473 |
NCBI Gene ID: | 11808 |
NCBI Accession: | NP_031494.2 |
UniProt Secondary Accession: | P06728,Q91XF8 |
UniProt Related Accession: | P06728 |
Molecular Weight: | |
NCBI Full Name: | apolipoprotein A-IV |
NCBI Synonym Full Names: | apolipoprotein A-IV |
NCBI Official Symbol: | Apoa4 |
NCBI Official Synonym Symbols: | Apoa-4 |
NCBI Protein Information: | apolipoprotein A-IV |
UniProt Protein Name: | Apolipoprotein A-IV |
UniProt Synonym Protein Names: | Apolipoprotein A4 |
Protein Family: | Apolipoprotein |
UniProt Gene Name: | Apoa4 |
UniProt Entry Name: |