Description
| Antibody Name: | Apoa4 Antibody (PACO24990) |
| Antibody SKU: | PACO24990 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Apolipoprotein A-IV protein (21-395AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. |
| Synonyms: | Apolipoprotein A-IV (Apo-AIV) (ApoA-IV) (Apolipoprotein A4), Apoa4 |
| UniProt Protein Function: | APOA4: May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. Synthesized primarily in the intestine and secreted in plasma. Belongs to the apolipoprotein A1/A4/E family.Protein type: Cell adhesion; Endoplasmic reticulum; Lipid-binding; Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 9 A5.2|9 25.36 cMCellular Component: cell surface; chylomicron; extracellular matrix; extracellular region; extracellular spaceMolecular Function: antioxidant activity; cholesterol binding; cholesterol transporter activity; copper ion binding; lipid binding; phosphatidylcholine binding; protein homodimerization activityBiological Process: cholesterol biosynthetic process; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; hydrogen peroxide catabolic process; innate immune response in mucosa; leukocyte adhesion; lipid homeostasis; lipid transport; lipoprotein metabolic process; multicellular organismal lipid catabolic process; neuron projection regeneration; phosphatidylcholine metabolic process; phospholipid efflux; positive regulation of fatty acid biosynthetic process; positive regulation of lipoprotein lipase activity; protein-lipid complex assembly; regulation of cholesterol transport; regulation of intestinal cholesterol absorption; removal of superoxide radicals; response to lipid hydroperoxide; reverse cholesterol transport; transport; triglyceride catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P06728 |
| NCBI GenInfo Identifier: | 110347473 |
| NCBI Gene ID: | 11808 |
| NCBI Accession: | NP_031494.2 |
| UniProt Secondary Accession: | P06728,Q91XF8 |
| UniProt Related Accession: | P06728 |
| Molecular Weight: | |
| NCBI Full Name: | apolipoprotein A-IV |
| NCBI Synonym Full Names: | apolipoprotein A-IV |
| NCBI Official Symbol: | Apoa4 |
| NCBI Official Synonym Symbols: | Apoa-4 |
| NCBI Protein Information: | apolipoprotein A-IV |
| UniProt Protein Name: | Apolipoprotein A-IV |
| UniProt Synonym Protein Names: | Apolipoprotein A4 |
| Protein Family: | Apolipoprotein |
| UniProt Gene Name: | Apoa4 |
| UniProt Entry Name: |