Antibody Name:	Apoa1 Antibody (PACO64139)
Antibody SKU:	PACO64139
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	WB:1:1000-1:5000
Species Reactivity:	Rat
Immunogen:	Recombinant Rat Apoa1 protein (19-259AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Antigen Affinity purified & Affinity purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Western Blot. Positive WB detected in: Rat Heart tissue, Rat Liver tissue, Rat Spleen tissue, Rat Lung tissue, Rat Kidney tissue, Rat Brain tissue, Rat Stomach tissue. All lanes: Apoa1 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 31 kDa. Observed band size: 31 kDa.

Background:	Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
Synonyms:	Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I)], Apoa1

UniProt Protein Function:	Function: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
UniProt Protein Details:	Subunit structure: Interacts with APOA1BP and CLU. Component of a sperm activating protein complex (SPAP), consisting of APOA1, an immunoglobulin heavy chain, an immunoglobulin light chain and albumin Subcellular location: Secreted. Tissue specificity: Major protein of plasma HDL, also found in chylomicrons. Post-translational modification: Phosphorylation sites are present in the extracelllular medium Sequence similarities: Belongs to the apolipoprotein A1/A4/E family.
NCBI Summary:	major component of high density lipoprotein (HDL) that is involved in intercellular cholesterol transport in astrocytes; cofactor for lecithin cholesterolacyltransferase (LCAT) [RGD]
UniProt Code:	P04639
NCBI GenInfo Identifier:	6978515
NCBI Gene ID:	25081
NCBI Accession:	NP_036870.1
UniProt Secondary Accession:	P04639,O08877, O09054, Q5EBB2,
UniProt Related Accession:	P04639
Molecular Weight:
NCBI Full Name:	apolipoprotein A-I preproprotein
NCBI Synonym Full Names:	apolipoprotein A-I
NCBI Official Symbol:	Apoa1
NCBI Official Synonym Symbols:	apoA-I
NCBI Protein Information:	apolipoprotein A-I; apo-AI; apolipoprotein A1; apolipoprotein A-1; preproapolipoprotein A-I
UniProt Protein Name:	Apolipoprotein A-I
UniProt Synonym Protein Names:	Apolipoprotein A1
Protein Family:	Apolipoprotein
UniProt Gene Name:	Apoa1
UniProt Entry Name:	APOA1_RAT