APC Anti-Rat CD161 Antibody [3.2.3]
- SKU:
- AGEL3429
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Rat
- Host Species:
- Mouse
- Isotype:
- Mouse IgG1, k
- Clone:
- 3.2.3
- Conjugation:
- APC
Description
| Product Name: | APC Anti-Rat CD161 Antibody [3.2.3] |
| Product Code: | AGEL3429 |
| Size: | 50 Tests, 100 Tests, 200 Tests |
| Clone No: | 3.2.3 |
| Synonyms: | NKR-P1, CD161a/CD161b, NKR-P1a/KLRB1a |
| Reactivity: | Rat |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG1, κ |
| Isotype Control: | APC Mouse IgG1, κ Isotype Control [MOPC-21] |
| Conjugation: | APC |
| Applications: | FCM |
| Recommended Dilution: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Fluorescent Label: | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Shipping: | Biological ice pack at 4°C |
| Form: | Liquid |
| Gene ID: | 362443 |
| Swissprot: | P27471,A4KWA1,Q5NKN4,Q5NKN2 |
| Background Information: | CD161 is a 30 kD type II transmembrane C-type lectin, expressed as a homodimer. Rat NKR-P1 receptors are primarily expressed on NK cells, a subset of T cells, dendritic cells, and activated monocytes. There are three different types of NKR-P in rat, namely NKR-P1a, NKR-P1b, and NKR-P1c. NKR-P1a does not contain an ITIM structure and is an activating receptor, while NKR-P1b contains an ITIM and displays inhibitory function. LLT-1 (ligand lectin like transcript 1) is the ligand, while KLR (killer cell lectin like) functions as a receptor. |
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