APC Anti-Mouse IL-17A Antibody [17F3] (AGEL3104)
- SKU:
- AGEL3104
Description
| Product Name: | APC Anti-Mouse IL-17A Antibody [17F3] (AGEL3104) |
| Product Code: | AGEL3104 |
| Clone No: | 17F3 |
| Synonyms: | Interleukin-17A,Il17a,Ctla8 |
| Reactivity: | Mouse |
| Host Species: | Mouse |
| Applications: | ICFCM |
| Isotype: | Mouse IgG1, κ |
| Isotype Control: | APC Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2564) |
| Conjugation: | APC |
| Form: | Liquid |
| Fluorescent Label: | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Gene ID: | 16171 |
| Swissprot: | Q62386 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-22A in vivo.
Additional Information
Product Type: |
Antibody |
Antibody Type: |
Monoclonal Antibody |
Applications: |
ICFCM |
Reactivity: |
Mouse |
Host Species: |
Mouse |
Isotype: |
Mouse IgG1, κ |
Clone: |
17F3 |
Conjugation: |
APC |
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