APC Anti-Mouse CD45.1 Antibody [A20]
- SKU:
- AGEL2311
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Mouse
- Host Species:
- Mouse
- Isotype:
- Mouse IgG2a, κ
- Clone:
- A20
- Conjugation:
- APC
Description
Product Name: | APC Anti-Mouse CD45.1 Antibody [A20] |
Product Code: | AGEL2311 |
Clone No: | A20 |
Synonyms: | Ly-5,L-CA,T200,CD45,Ptprc |
Reactivity: | Mouse |
Host Species: | Mouse |
Applications: | FCM |
Isotype: | Mouse IgG2a, κ |
Isotype Control: | APC Mouse IgG2a, κ Isotype Control [C1.18.4] (AGEL2574) |
Conjugation: | APC |
Form: | Liquid |
Fluorescent Label: | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Shipping: | Biological ice pack at 4°C |
CD45.1 is an alloantigen of CD45, expressed by Ly5.1 bearing mouse strains (e.g., RIII, SJL/J, STS/A, DA). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in mice that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell types. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.