APC Anti-Human/Mouse IL-5 Antibody [TRFK5] (AGEL3283)

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SKU:
AGEL3283
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
ICFCM
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG1, k
Clone:
TRFK5
Conjugation:
APC

Description

Product Name:APC Anti-Human/Mouse IL-5 Antibody [TRFK5]
Product Code:AGEL3283
Size:25ug, 100ug
Clone No:TRFK5
Synonyms:Interleukin-5, IL-5, B-cell differentiation factor I, T-cell replacing factor, TRF
Reactivity:Human,Mouse
Host Species:Rat
Applications:ICFCM
Isotype:Rat IgG1, κ
Isotype Control:APC Rat IgG1, κ Isotype Control [HRPN]
Conjugation:APC
Applications:ICFCM
Recommended Dilution:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Fluorescent Label:APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Shipping:Biological ice pack at 4°C
Form:Liquid
Swissprot:P05113,P04401
Background Information:IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.
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