APC Anti-Human/Mouse IL-5 Antibody [TRFK5] (AGEL3281)
- SKU:
- AGEL3281
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- ICFCM
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- Rat IgG1, k
- Clone:
- TRFK5
- Conjugation:
- APC
Description
Product Name: | APC Anti-Human/Mouse IL-5 Antibody [TRFK5] |
Product Code: | AGEL3281 |
Size: | 20 Tests, 100 Tests, 200 Tests |
Clone No: | TRFK5 |
Synonyms: | Interleukin-5, IL-5, B-cell differentiation factor I, T-cell replacing factor, TRF |
Reactivity: | Human,Mouse |
Host Species: | Rat |
Applications: | ICFCM |
Isotype: | Rat IgG1, κ |
Isotype Control: | APC Rat IgG1, κ Isotype Control [HRPN] |
Conjugation: | APC |
Applications: | ICFCM |
Recommended Dilution: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Fluorescent Label: | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
Shipping: | Biological ice pack at 4°C |
Form: | Liquid |
Swissprot: | P05113,P04401 |
Background Information: | IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5. |