APC Anti-Human CD80 Antibody [2D10]
- SKU:
- AGEL2470
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- Mouse IgG1, κ
- Clone:
- 2D10
- Conjugation:
- APC
Description
| Product Name: | APC Anti-Human CD80 Antibody [2D10] |
| Product Code: | AGEL2470 |
| Clone No: | 2D10 |
| Synonyms: | T-lymphocyte activation antigen CD80,B7-1, B7, BB1 |
| Reactivity: | Human |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG1, κ |
| Isotype Control: | APC Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2551) |
| Conjugation: | APC |
| Form: | Liquid |
| Fluorescent Label: | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Swissprot: | P33681 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Related Products
PE Anti-Human CD80 Antibody [2D10]
OverviewProduct Name:PE Anti-Human CD80 Antibody [2D10]Product Code:AGEL2469Clone No:2D10Synonyms:T-lymphocyte activation antigen
PE/Cyanine7 Anti-Human CD80 Antibody [2D10]
OverviewProduct Name:PE/Cyanine7 Anti-Human CD80 Antibody [2D10]Product Code:AGEL2759Clone No:2D10Synonyms:T-lymphocyte activatio
APC Anti-Human CD62L Antibody [HI62L]
OverviewProduct Name:APC Anti-Human CD62L Antibody [HI62L]Product Code:AGEL3486Size:20 Tests, 100 Tests, 200 TestsClone No:HI62L<
APC Anti-Human CD20 Antibody [2H7]
OverviewProduct Name:APC Anti-Human CD20 Antibody [2H7]Product Code:AGEL2394Clone No:2H7Synonyms:Bp35,Leukocyte surface antigen L