AP3M2 Antibody (PACO24956)
- SKU:
- PACO24956
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AP3M2 Antibody (PACO24956) |
| Antibody SKU: | PACO24956 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human AP-3 complex subunit mu-2 protein (1-273AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO24956 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO24956 at dilution of 1:100. |
| Background: | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
| Synonyms: | AP-3 complex subunit mu-2 (Adaptor-related protein complex 3 subunit mu-2) (Clathrin assembly protein assembly protein complex 3 mu-2 medium chain) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Mu3B-adaptin) (P47B), AP3M2 |
| UniProt Protein Function: | AP3M2: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Belongs to the adaptor complexes medium subunit family.Chromosomal Location of Human Ortholog: 8p11.2Cellular Component: Golgi apparatus; cytoplasmic vesicle membrane; clathrin adaptor complex; AP-type membrane coat adaptor complexBiological Process: intracellular protein transport; anterograde synaptic vesicle transport; anterograde axon cargo transport |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 3 (AP-3), which belongs to the adaptor complexes medium subunits family. The AP-3 complex plays a role in protein trafficking to lysosomes and specialized organelles. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2008] |
| UniProt Code: | P53677 |
| NCBI GenInfo Identifier: | 197209857 |
| NCBI Gene ID: | 10947 |
| NCBI Accession: | NP_001127768.1 |
| UniProt Secondary Accession: | P53677,Q7Z472, B2RCR0, D3DSY2 |
| UniProt Related Accession: | P53677 |
| Molecular Weight: | 46,977 Da |
| NCBI Full Name: | AP-3 complex subunit mu-2 |
| NCBI Synonym Full Names: | adaptor-related protein complex 3, mu 2 subunit |
| NCBI Official Symbol: | AP3M2 |
| NCBI Official Synonym Symbols: | P47B; AP47B; CLA20 |
| NCBI Protein Information: | AP-3 complex subunit mu-2; mu3B-adaptin; HA1 47kDA subunit homolog 2; HA1 47 kDa subunit homolog 2; clathrin-associated protein AP47 homolog 2; golgi adaptor AP-1 47 kDA protein homolog 2; clathrin coat assembly protein AP47 homolog 2; adapter-related protein complex 3 mu-2 subunit; adapter-related protein complex 3 subunit mu-2; clathrin coat-associated protein AP47 homolog 2; clathrin assembly protein assembly protein complex 3 mu-2 medium chain; clathrin assembly protein assembly protein complex 1 medium chain homolog 2 |
| UniProt Protein Name: | AP-3 complex subunit mu-2 |
| UniProt Synonym Protein Names: | Adaptor-related protein complex 3 subunit mu-2; Clathrin assembly protein assembly protein complex 3 mu-2 medium chain; Clathrin coat assembly protein AP47 homolog 2; Clathrin coat-associated protein AP47 homolog 2; Golgi adaptor AP-1 47 kDa protein homolog 2; HA1 47 kDa subunit homolog 2; Mu3B-adaptin; P47B |
| Protein Family: | AP-3 complex |
| UniProt Gene Name: | AP3M2 |
| UniProt Entry Name: | AP3M2_HUMAN |
| Antibodies |
| AP3M2 Antibody (PACO07771) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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