ANXA1 Monoclonal Antibody [PAT2G5AT] (CPAB0625)

Name: ANXA1 Monoclonal Antibody [PAT2G5AT] (CPAB0625)
SKU: CPAB0625
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system_update_alt Datasheet Overview

system_update_alt Datasheet Overview

OverviewProduct Name:ANXA1 Polyclonal AntibodyProduct Code:CAB0767Reactivity:Human, RatApplications:Western blotting, Immunohisto

Product Name:	ANXA1 Antibody
Product Sku:	CPAB0625
Size:	5μg
Host Species:	Mouse
Immunogen:	Anti-human ANXA1 mAb, clone PAT2G5AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ANXA1 protein 1-346 amino acids purified from Ecoli.
Clone:	PAT2G5AT
Reactivity:	Other bodies
Applications:	Western Blot, ELISA

Purification Method:	ANXA1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:	IgG2a
Background:	ANXA1 is part of the family of Ca(2+)-dependent phospholipid binding proteins which have a Mw between 35kDa-40kDa and are situated on the cytosolic face of the plasma membrane. ANXA1 protein has a Mw of 40kDa, with phospholipase A2 inhibitory activity to bind from two to four calcium ions with high affinity. Since phospholipase A2 is necessary for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, ANXA1 might have potential anti-inflammatory activity. ANXA1 promotes membrane fusion and iplays a role in exocytosis. The recognition of ANXA1 protein by immunocytochemical leads a simple, highly sensitive and specific assay for diagnosis of hairy cell leukemia.
Synonyms:	ANX1, LPC1, ANXA1, Lipocortin I, Calpactin II, Chrombindin-9, p35, Annexin-1, Phospholipase A2 inhibitory protein, Annexin I, Annexin A1.
Storage Buffer:	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.