Epigenetics & Nuclear Signaling Antibodies 2

Anti-ZNF644 Antibody (CAB16154)

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SKU:
CAB16154
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-ZNF644 Antibody
Antibody SKU:CAB16154
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ZNF644 (NP_958357.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ZNF644 (NP_958357.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MRSF LQQD VNKT KSRL NVLN GLAN NMDD LKIN TDIT GAKE ELLD DNNF ISDK ESGV HKPK DCQT SFQK NNTL TLPE ELSK DKSE NALS GGQS SLFI HAGA PTVS SENF ILPK GAAV NGPV SHSS LTKT SNMN KGSV SLTT GQPV DQPT TESC STLK VAAD LQLS TPQK ASQH QVLF LLSD VAHA KNPT HSNK KLPT SASV GCDI QNSV GSNI KSDG TLIN QVEV GEDG EDLL VKDD CVNT VTGI SSGT DGFR SEND TNWD PQKE FIQF LMTN EETV DKAP PHSK IGLE KKRK RKMD VSKI
Gene ID:84146
Uniprot:Q9H582
Cellular Location:Nucleus
Calculated MW:11kDa/139kDa/149kDa
Observed MW:150kDa
Synonyms:ZNF644, BM-005, MYP21, NatF, ZEP-2
Background:The protein encoded by this gene is a zinc finger transcription factor that may play a role in eye development. Defects in this gene have been associated with high myopia. Three transcript variants encoding two different isoforms have been found for this gene.
UniProt Protein Function:ZNF644: May be involved in transcriptional regulation. Defects in ZNF644 are the cause of myopia type 21 (MYP21). A refractive error of the eye, in which parallel rays from a distant object come to focus in front of the retina, vision being better for near objects than for far. Belongs to the krueppel C2H2-type zinc-finger protein family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:C2H2-type zinc finger protein; Transcription factor

Chromosomal Location of Human Ortholog: 1p22.2

Cellular Component: nucleus

Molecular Function:DNA binding; metal ion binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent

Disease: Myopia 21, Autosomal Dominant

NCBI Summary:The protein encoded by this gene is a zinc finger transcription factor that may play a role in eye development. Defects in this gene have been associated with high myopia. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
UniProt Code:Q9H582
NCBI GenInfo Identifier:41152095
NCBI Gene ID:84146
NCBI Accession:NP_057704.2
UniProt Related Accession:Q9H582
Molecular Weight:Calculated: 11kDa; 139kDa; 149kDaObserved: 150kDa
NCBI Full Name:zinc finger protein 644 isoform 2
NCBI Synonym Full Names:zinc finger protein 644
NCBI Official Symbol:ZNF644  
NCBI Official Synonym Symbols:NatF; MYP21; ZEP-2; BM-005  
NCBI Protein Information:zinc finger protein 644
UniProt Protein Name:Zinc finger protein 644
UniProt Synonym Protein Names:Zinc finger motif enhancer-binding protein 2; Zep-2
Protein Family:Zinc finger protein
UniProt Gene Name:ZNF644  
UniProt Entry Name:ZN644_HUMAN
Anti-ZNF644 Antibody (CAB16154)Western blot analysis of extracts of mouse liver, using ZNF644 antibody (CAB16154) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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