Epigenetics & Nuclear Signaling Antibodies 4

Anti-ZNF408 Antibody (CAB8512)

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SKU:
CAB8512
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-ZNF408 Antibody
Antibody SKU:CAB8512
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 471-720 of human ZNF408 (NP_079017.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:A-549, HepG2, HeLa, MCF7, Mouse liver, Mouse spleen, Mouse thymus, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 471-720 of human ZNF408 (NP_079017.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PVCG RPLA NQGS LRNH MRLH TGEK PFLC PHCG RAFR QRGN LRGH LRLH TGER PYRC PHCA DAFP QLPE LRRH LISH TGEA HLCP VCGK ALRD PHTL RAHE RLHS GERP FPCP QCGR AYTL ATKL RRHL KSHL EDKP YRCP TCGM GYTL PQSL RRHQ LSHR PEAP CSPP SVPS AASE PTVV LLQA EPQL LDTH REEE VSPA RDVV EVTI SESQ EKCF VVPE EPDA APSL VLIH KDMG LGAW AEVV EVEM GT
Gene ID:79797
Uniprot:Q9H9D4
Cellular Location:Nucleus
Calculated MW:78kDa
Observed MW:78kDa
Synonyms:ZNF408, EVR6, RP72
Background:The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP).
UniProt Protein Function:ZNF408: May be involved in transcriptional regulation.
UniProt Protein Details:

Protein type:C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 11p11.2

Cellular Component: nucleus

Molecular Function:identical protein binding; protein binding

Disease: Exudative Vitreoretinopathy 6; Retinitis Pigmentosa 72

UniProt Code:Q9H9D4
NCBI GenInfo Identifier:17368963
NCBI Gene ID:79797
NCBI Accession:Q9H9D4.1
UniProt Related Accession:Q9H9D4
Molecular Weight:78,439 Da
NCBI Full Name:Zinc finger protein 408
NCBI Synonym Full Names:zinc finger protein 408
NCBI Official Symbol:ZNF408  
NCBI Official Synonym Symbols:EVR6; RP72  
NCBI Protein Information:zinc finger protein 408
UniProt Protein Name:Zinc finger protein 408
UniProt Synonym Protein Names:PR domain zinc finger protein 17
Protein Family:Zinc finger protein
UniProt Gene Name:ZNF408  
UniProt Entry Name:ZN408_HUMAN
Anti-ZNF408 Polyclonal Antibody (CAB8512)Western blot analysis of extracts of various cell lines, using ZNF408 antibody (CAB8512) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 1s.
Anti-ZNF408 Polyclonal Antibody (CAB8512)Immunohistochemistry of paraffin-embedded rat lung using ZNF408 antibody (CAB8512) at dilution of 1:100 (40x lens).
Anti-ZNF408 Polyclonal Antibody (CAB8512)Immunohistochemistry of paraffin-embedded mouse liver using ZNF408 antibody (CAB8512) at dilution of 1:100 (40x lens).
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