Epigenetics & Nuclear Signaling Antibodies 2
Anti-ZNF408 Antibody (CAB15190)
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- SKU:
- CAB15190
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-ZNF408 Antibody |
| Antibody SKU: | CAB15190 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ZNF408 (NP_079017.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ZNF408 (NP_079017.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEEA EELL LEGK KALQ LARE PRLG LDLG WNPS GEGC TQGL KDVP PEPT RDIL ALKS LPRG LALG PSLA KEQR LGVW CVGD PLQP GLLW GPLE EESA SKEK GEGV KPRQ EENL SLGP WGDV CACE QSSG WTSL VQRG RLES EGNV APVR ISER LHLQ VYQL VLPG SELL LWPQ PSSE GPSL TQPG LDKE AAVA VVTE VESA VQQE VASP GEDA AEPC IDPG SQSP SGIQ AENM VSPG LKFP |
| Gene ID: | 79797 |
| Uniprot: | Q9H9D4 |
| Cellular Location: | Nucleus |
| Calculated MW: | 78kDa |
| Observed MW: | Refer to figures |
| Synonyms: | ZNF408, EVR6, RP72 |
| Background: | The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP). |
| UniProt Protein Function: | ZNF408: May be involved in transcriptional regulation. |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 11p11.2 Cellular Component: nucleus Molecular Function:identical protein binding; protein binding Disease: Exudative Vitreoretinopathy 6; Retinitis Pigmentosa 72 |
| UniProt Code: | Q9H9D4 |
| NCBI GenInfo Identifier: | 17368963 |
| NCBI Gene ID: | 79797 |
| NCBI Accession: | Q9H9D4.1 |
| UniProt Related Accession: | Q9H9D4 |
| Molecular Weight: | 78,439 Da |
| NCBI Full Name: | Zinc finger protein 408 |
| NCBI Synonym Full Names: | zinc finger protein 408 |
| NCBI Official Symbol: | ZNF408 |
| NCBI Official Synonym Symbols: | EVR6; RP72 |
| NCBI Protein Information: | zinc finger protein 408 |
| UniProt Protein Name: | Zinc finger protein 408 |
| UniProt Synonym Protein Names: | PR domain zinc finger protein 17 |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | ZNF408 |
| UniProt Entry Name: | ZN408_HUMAN |
 | Immunofluorescence analysis of Hela cells using ZNF408 antibody (CAB15190) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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