Epigenetics & Nuclear Signaling Antibodies 4

Anti-ZNF350 Antibody (CAB7829)

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SKU:
CAB7829
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-ZNF350 Antibody
Antibody SKU:CAB7829
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 233-532 of human ZNF350 (NP_067645.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:Jurkat, THP-1, Mouse thymus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 233-532 of human ZNF350 (NP_067645.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PHRC SLCE KAFS RKFM LTEH QRTH TGEK PYEC PECG KAFL KKSR LNIH QKTH TGEK PYIC SECG KGFI QKGN LIVH QRIH TGEK PYIC NECG KGFI QKTC LIAH QRFH TGKT PFVC SECG KSCS QKSG LIKH QRIH TGEK PFEC SECG KAFS TKQK LIVH QRTH TGER PYGC NECG KAFA YMSC LVKH KRIH TREK QEAA KVEN PPAE RHSS LHTS DVMQ EKNS ANGA TTQV PSVA PQTS LNIS GLLA NRNV VLVG QPVV RCAA SGDN RGFA QDRN LVNA VNVV VPSV INYV LFYV TENP
Gene ID:59348
Uniprot:Q9GZX5
Cellular Location:Nucleus, Nucleus matrix
Calculated MW:60kDa
Observed MW:60kDa
Synonyms:ZNF350, ZBRK1, ZFQR
Background:
UniProt Protein Function:ZNF350: Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3. Belongs to the krueppel C2H2-type zinc-finger protein family.
UniProt Protein Details:

Protein type:C2H2-type zinc finger protein; Transcription factor

Chromosomal Location of Human Ortholog: 19q13.41

Cellular Component: nucleoplasm; nucleus; transcriptional repressor complex

Molecular Function:DNA binding; protein binding

Biological Process: negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent

UniProt Code:Q9GZX5
NCBI GenInfo Identifier:313104255
NCBI Gene ID:59348
NCBI Accession:Q9GZX5.3
UniProt Secondary Accession:Q9GZX5,Q96G73, Q9HAQ4,
UniProt Related Accession:Q9GZX5
Molecular Weight:60,011 Da
NCBI Full Name:Zinc finger protein 350
NCBI Synonym Full Names:zinc finger protein 350
NCBI Official Symbol:ZNF350  
NCBI Official Synonym Symbols:ZFQR; ZBRK1  
NCBI Protein Information:zinc finger protein 350
UniProt Protein Name:Zinc finger protein 350
UniProt Synonym Protein Names:KRAB zinc finger protein ZFQR; Zinc finger and BRCA1-interacting protein with a KRAB domain 1; Zinc finger protein ZBRK1
Protein Family:Zinc finger protein
UniProt Gene Name:ZNF350  
UniProt Entry Name:ZN350_HUMAN
Anti-ZNF350 Antibody (CAB7829)Western blot analysis of extracts of various cell lines, using ZNF350 antibody (CAB7829) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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