Epigenetics & Nuclear Signaling Antibodies 2

Anti-ZNF331 Antibody (CAB15470)

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SKU:
CAB15470
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-ZNF331 Antibody
Antibody SKU:CAB15470
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human ZNF331 (NP_061025.5).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse testis, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human ZNF331 (NP_061025.5).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AYEN KSLP TEKN IHEI RASK RNSD RRSK SLGR NWIC EGTL ERPQ RSRG RYVN QMII NYVK RPAT REGT PPRT HQRH HKEN S
Gene ID:55422
Uniprot:Q9NQX6
Cellular Location:Nucleus
Calculated MW:53kDa
Observed MW:56kDa
Synonyms:ZNF331, RITA, ZNF361, ZNF463
Background:This gene encodes a zinc finger protein containing a KRAB (Kruppel-associated box) domain found in transcriptional repressors. This gene may be methylated and silenced in cancer cells. This gene is located within a differentially methylated region (DMR) and shows allele-specific expression in placenta. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding the same protein.
UniProt Protein Function:ZNF331: May be involved in transcriptional regulation. May play a role in spermatogenesis. Belongs to the krueppel C2H2-type zinc-finger protein family.
UniProt Protein Details:

Protein type:Transcription factor; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: nucleus

Biological Process: regulation of transcription, DNA-dependent

NCBI Summary:This gene encodes a zinc finger protein containing a KRAB (Kruppel-associated box) domain found in transcriptional repressors. This gene may be methylated and silenced in cancer cells. This gene is located within a differentially methylated region (DMR) and shows allele-specific expression in placenta. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding the same protein. [provided by RefSeq, Nov 2015]
UniProt Code:Q9NQX6
NCBI GenInfo Identifier:34925661
NCBI Gene ID:55422
NCBI Accession:Q9NQX6.1
UniProt Secondary Accession:Q9NQX6,Q96GJ4,
UniProt Related Accession:Q9NQX6
Molecular Weight:53,739 Da
NCBI Full Name:Zinc finger protein 331
NCBI Synonym Full Names:zinc finger protein 331
NCBI Official Symbol:ZNF331  
NCBI Official Synonym Symbols:RITA; ZNF361; ZNF463  
NCBI Protein Information:zinc finger protein 331
UniProt Protein Name:Zinc finger protein 331
UniProt Synonym Protein Names:C2H2-like zinc finger protein rearranged in thyroid adenomas; Zinc finger protein 361; Zinc finger protein 463
Protein Family:Zinc finger protein
UniProt Gene Name:ZNF331  
UniProt Entry Name:ZN331_HUMAN
Anti-ZNF331 Antibody (CAB15470)Western blot analysis of extracts of various cell lines, using ZNF331 antibody (CAB15470) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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