Epigenetics & Nuclear Signaling Antibodies 2
Anti-ZNF174 Antibody (CAB14801)
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- SKU:
- CAB14801
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-ZNF174 Antibody |
| Antibody SKU: | CAB14801 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human ZNF174 (NP_001027463.1). |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:200 |
| Reactivity: | Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human ZNF174 (NP_001027463.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAAK MEIT LSSN TEAS SKQE RHII AKLE EKRG PPLQ KNCP DPEL CRQS FRRF CYQE VSGP QEAL SQLR QLCR QWLQ PELH TKEQ ILEL LVME QFLT ILPP EIQA RVRH RCPM SSKE IVTL VEDF HRAS KKPK QWVA VCMQ GQKV LLEK TGSQ LGEQ ELPD FQPQ TPRR DLRE SSPA EPSQ AGAY DRLS PHHW EKSP LLQE PTPK LAGT ELLI EKTD PNMA TDEL PCKL WLSF IA |
| Gene ID: | 7727 |
| Uniprot: | Q15697 |
| Cellular Location: | Nucleus |
| Calculated MW: | 26kDa/46kDa |
| Observed MW: |
| Synonyms: | ZNF174, ZSCAN8 |
| Background: | This gene encodes a protein with three Cys2-His2-type zinc fingers in the carboxy-terminus, a putative nuclear localization signal, and an amino-terminus SCAN box which forms homodimers. This protein is believed to function as a transcriptional repressor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| UniProt Protein Function: | ZNF174: a transcriptional repressor of the krueppel C2H2-type zinc-finger protein family. Two splice variant isoforms have been described. |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: actin cytoskeleton; cytoplasm; nucleoplasm; nucleus Molecular Function:protein homodimerization activity; transcription factor activity Biological Process: negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent |
| UniProt Code: | Q15697 |
| NCBI GenInfo Identifier: | 3123173 |
| NCBI Gene ID: | 7727 |
| NCBI Accession: | Q15697.1 |
| UniProt Secondary Accession: | Q15697,Q53Y68, Q9BQ34, |
| UniProt Related Accession: | Q15697 |
| Molecular Weight: | 26,884 Da |
| NCBI Full Name: | Zinc finger protein 174 |
| NCBI Synonym Full Names: | zinc finger protein 174 |
| NCBI Official Symbol: | ZNF174 |
| NCBI Official Synonym Symbols: | ZSCAN8 |
| NCBI Protein Information: | zinc finger protein 174 |
| UniProt Protein Name: | Zinc finger protein 174 |
| UniProt Synonym Protein Names: | AW-1; Zinc finger and SCAN domain-containing protein 8 |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | ZNF174 |
| UniProt Entry Name: | ZN174_HUMAN |
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