Epigenetics & Nuclear Signaling Antibodies 2

Anti-ZNF124 Antibody (CAB15111)

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SKU:
CAB15111
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-ZNF124 Antibody
Antibody SKU:CAB15111
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-200 of human ZNF124 (NP_001284497.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:mouse brain, rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-200 of human ZNF124 (NP_001284497.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SIED QYKN SSRN LRHI ISHS GNNP YGCE ECGK KPCT CKQC QKTS LSVT RVHR DTVM HTGN GHYG CTIC EKVF NIPS SFQI HQRN HTGE KPYE CMEC GKAL GFSR SLNR HKRI HTGE KRYE CKQC GKAF SRSS HLRD HERT H
Gene ID:7678
Uniprot:Q15973
Cellular Location:Nucleus
Calculated MW:8kDa/17kDa/33kDa/40kDa
Observed MW:50kDa
Synonyms:ZNF124, HZF-16, HZF16, ZK7
Background:This gene encodes a protein with an amino-terminal KRAB-A box and multiple repeated Kruppel-type (C2H2) zinc finger motifs at its carboxy terminus. The encoded protein may function as a transcription factor. Expression of this gene is increased after vascular endothelial growth factor (VEGF) stimulation in human leukemia cell lines and results in inhibition of apoptotic cell death induced by irradiation or exposure to etoposide. Alternative splicing results in multiple transcript variants encoding distinct proteins.
UniProt Protein Function:ZNF124: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:DNA-binding; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 1q44

Molecular Function:protein binding

NCBI Summary:This gene encodes a protein with an amino-terminal KRAB-A box and multiple repeated Kruppel-type (C2H2) zinc finger motifs at its carboxy terminus. The encoded protein may function as a transcription factor. Expression of this gene is increased after vascular endothelial growth factor (VEGF) stimulation in human leukemia cell lines and results in inhibition of apoptotic cell death induced by irradiation or exposure to etoposide. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2014]
UniProt Code:Q15973
NCBI GenInfo Identifier:76803836
NCBI Gene ID:7678
NCBI Accession:Q15973.2
UniProt Secondary Accession:Q15973,Q15974, Q4VAJ7, Q5T2V4, B3KNP3, J3KSE1,
UniProt Related Accession:Q15973
Molecular Weight:8,411 Da
NCBI Full Name:Zinc finger protein 124
NCBI Synonym Full Names:zinc finger protein 124
NCBI Official Symbol:ZNF124  
NCBI Official Synonym Symbols:ZK7; HZF16; HZF-16  
NCBI Protein Information:zinc finger protein 124
UniProt Protein Name:Zinc finger protein 124
UniProt Synonym Protein Names:Zinc finger protein HZF-16
Protein Family:Zinc finger protein
UniProt Gene Name:ZNF124  
UniProt Entry Name:ZN124_HUMAN
Anti-ZNF124 Antibody (CAB15111)Western blot analysis of extracts of various cell lines, using ZNF124 antibody (CAB15111) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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