Epigenetics & Nuclear Signaling Antibodies 1

Anti-ZNF12 Antibody (CAB13783)

(No reviews yet) Write a Review
SKU:
CAB13783
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-ZNF12 Antibody
Antibody SKU:CAB13783
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 70-240 of human ZNF12 (NP_057349.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Mouse, Rat
Positive Samples:Mouse lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 70-240 of human ZNF12 (NP_057349.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:EGEF LLQS YPDE VWQT DDLI ERIQ EEEN KPSR QTVF IETL IEER GNVP GKTF DVET NPVP SRKI AYKN SLCD SCEK CLTS VSEY ISSD GSYA RMKA DECS GCGK SLLH IKLE KTHP GDQA YEFN QNGE PYTL NEES LYQK IRIL EKPF EYIE CQKA FQKD TVFV NHME EKP
Gene ID:7559
Uniprot:P17014
Cellular Location:Nucleus
Calculated MW:54kDa/58kDa/72kDa/77kDa/81kDa
Observed MW:81kDa
Synonyms:ZNF12, GIOT-3, HZF11, KOX3, ZNF325
Background:This gene is a member of the krueppel C2H2-type zinc-finger protein family and encodes a protein with eight C2H2-type zinc fingers and a KRAB domain. This nuclear protein is involved in developmental control of gene expression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
UniProt Protein Function:ZNF12: Transcriptional repressor which suppresses activation protein 1 (AP-1)- and serum response element (SRE)-mediated transcriptional activity. Belongs to the krueppel C2H2-type zinc-finger protein family. 5 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 7p22.1

Cellular Component: centrosome; nucleoplasm; nucleus

Molecular Function:transcription factor activity

Biological Process: negative regulation of transcription, DNA-dependent

NCBI Summary:This gene is a member of the krueppel C2H2-type zinc-finger protein family and encodes a protein with eight C2H2-type zinc fingers and a KRAB domain. This nuclear protein is involved in developmental control of gene expression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
UniProt Code:P17014
NCBI GenInfo Identifier:317373491
NCBI Gene ID:7559
NCBI Accession:P17014.3
UniProt Secondary Accession:P17014,Q6N016, Q8NHZ0, Q9H9P0, Q9ULZ6, A8MYC4, A8WFQ8 B2RNQ7, B4DF45,
UniProt Related Accession:P17014
Molecular Weight:77,131 Da
NCBI Full Name:Zinc finger protein 12
NCBI Synonym Full Names:zinc finger protein 12
NCBI Official Symbol:ZNF12  
NCBI Official Synonym Symbols:KOX3; HZF11; GIOT-3; ZNF325  
NCBI Protein Information:zinc finger protein 12
UniProt Protein Name:Zinc finger protein 12
UniProt Synonym Protein Names:Gonadotropin-inducible ovary transcription repressor 3; GIOT-3; Zinc finger protein 325; Zinc finger protein KOX3
Protein Family:Zinc finger protein
UniProt Gene Name:ZNF12  
UniProt Entry Name:ZNF12_HUMAN
Anti-ZNF12 Antibody (CAB13783)Western blot analysis of extracts of mouse kidney, using ZNF12 Antibody (CAB13783) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
View AllClose

0 Reviews

View AllClose

Related Products