Description
| Product Name: | ZMAT3 Rabbit pAb |
| Product Code: | CAB4928 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | ZMAT3, PAG608, WIG-1, WIG1 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human ZMAT3 (NP_071915.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human ZMAT3 (NP_071915.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MILL QHAV LPPP KQPS PSPP MSVA TRST GTLQ LPPQ KPFG QEAS LPLA GEEE LSKG GEQD CALE ELCK PLYC KLCN VTLN SAQQ AQAH YQGK NHGK KLRN YYAA NSCP PPAR MSNV VEPA ATPV VPVP PQMG SFKP GGRV ILAT ENDY CKLC DASF SSPA VAQA HYQG KNHA KRLR LAEA QSNS FSES SELG QRRA RKEG NEFK MMPN RRNM YTVQ NNSA GPYF NPRS RQRI PRDL AMCV TPSG QFYC SMCN VGAG EEME FRQH LESK QHKS KVSE QRYR NEME NLGY V |
| Gene ID: | 64393 |
| Uniprot: | Q9HA38 |
| Cellular Location: | Nucleus, nucleolus |
| Calculated MW: | 31kDa/32kDa |
| Observed MW: | 32kDa |
| UniProt Protein Function: | ZMAT3: Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 3q26.32 Cellular Component: nucleolus Molecular Function:protein binding; zinc ion binding Biological Process: protein transport; apoptosis; positive regulation of apoptosis; regulation of growth; response to DNA damage stimulus |
| NCBI Summary: | This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9HA38 |
| NCBI GenInfo Identifier: | 74734128 |
| NCBI Gene ID: | 64393 |
| NCBI Accession: | Q9HA38.1 |
| UniProt Secondary Accession: | Q9HA38,Q96A21, B3KVA6, D3DNR1, |
| UniProt Related Accession: | Q9HA38 |
| Molecular Weight: | 289 |
| NCBI Full Name: | Zinc finger matrin-type protein 3 |
| NCBI Synonym Full Names: | zinc finger, matrin-type 3 |
| NCBI Official Symbol: | ZMAT3 |
| NCBI Official Synonym Symbols: | WIG1; WIG-1; PAG608 |
| NCBI Protein Information: | zinc finger matrin-type protein 3; ZMAT3; WIG-1/PAG608 protein; zinc finger protein WIG1; zinc finger protein WIG-1; zinc finger, matrin type 3; p53 target zinc finger protein; p53-activated gene 608 protein |
| UniProt Protein Name: | Zinc finger matrin-type protein 3 |
| UniProt Synonym Protein Names: | Zinc finger protein WIG-1; p53-activated gene 608 protein |
| Protein Family: | Zinc finger matrin-type protein |
| UniProt Gene Name: | ZMAT3 |
| UniProt Entry Name: | ZMAT3_HUMAN |
Additional Information
Product Type: |
Antibody |
Antibody Type: |
Polyclonal Antibody |
Reactivity: |
Human |
Reactivity: |
Mouse |
Reactivity: |
Rat |
Host Species: |
Rabbit |
Isotype: |
IgG |
Synonyms: |
ZMAT3 |
Synonyms: |
PAG608 |
Synonyms: |
WIG-1 |
Synonyms: |
WIG1 |
Research Area: |
Cell Death |
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