Cell Death Antibodies 2

Anti-ZMAT3 Antibody (CAB4928)

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SKU:
CAB4928
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ZMAT3
Synonyms:
PAG608
Synonyms:
WIG-1
Synonyms:
WIG1
Research Area:
Cell Death

Description

Product Name:ZMAT3 Rabbit pAb
Product Code:CAB4928
Size:20uL, 50uL, 100uL
Synonyms:ZMAT3, PAG608, WIG-1, WIG1
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human ZMAT3 (NP_071915.1).
Applications:WB
Recommended Dilutions:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human ZMAT3 (NP_071915.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MILL QHAV LPPP KQPS PSPP MSVA TRST GTLQ LPPQ KPFG QEAS LPLA GEEE LSKG GEQD CALE ELCK PLYC KLCN VTLN SAQQ AQAH YQGK NHGK KLRN YYAA NSCP PPAR MSNV VEPA ATPV VPVP PQMG SFKP GGRV ILAT ENDY CKLC DASF SSPA VAQA HYQG KNHA KRLR LAEA QSNS FSES SELG QRRA RKEG NEFK MMPN RRNM YTVQ NNSA GPYF NPRS RQRI PRDL AMCV TPSG QFYC SMCN VGAG EEME FRQH LESK QHKS KVSE QRYR NEME NLGY V
Gene ID:64393
Uniprot:Q9HA38
Cellular Location:Nucleus, nucleolus
Calculated MW:31kDa/32kDa
Observed MW:32kDa
UniProt Protein Function:ZMAT3: Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Nucleolus

Chromosomal Location of Human Ortholog: 3q26.32

Cellular Component: nucleolus

Molecular Function:protein binding; zinc ion binding

Biological Process: protein transport; apoptosis; positive regulation of apoptosis; regulation of growth; response to DNA damage stimulus

NCBI Summary:This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. [provided by RefSeq, Jul 2008]
UniProt Code:Q9HA38
NCBI GenInfo Identifier:74734128
NCBI Gene ID:64393
NCBI Accession:Q9HA38.1
UniProt Secondary Accession:Q9HA38,Q96A21, B3KVA6, D3DNR1,
UniProt Related Accession:Q9HA38
Molecular Weight:289
NCBI Full Name:Zinc finger matrin-type protein 3
NCBI Synonym Full Names:zinc finger, matrin-type 3
NCBI Official Symbol:ZMAT3  
NCBI Official Synonym Symbols:WIG1; WIG-1; PAG608  
NCBI Protein Information:zinc finger matrin-type protein 3; ZMAT3; WIG-1/PAG608 protein; zinc finger protein WIG1; zinc finger protein WIG-1; zinc finger, matrin type 3; p53 target zinc finger protein; p53-activated gene 608 protein
UniProt Protein Name:Zinc finger matrin-type protein 3
UniProt Synonym Protein Names:Zinc finger protein WIG-1; p53-activated gene 608 protein
Protein Family:Zinc finger matrin-type protein
UniProt Gene Name:ZMAT3  
UniProt Entry Name:ZMAT3_HUMAN
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