Epigenetics & Nuclear Signaling Antibodies 3

Anti-ZGPAT Antibody (CAB16583)

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SKU:
CAB16583
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-ZGPAT Antibody
Antibody SKU:CAB16583
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 212-511 of human ZGPAT (NP_852150.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 212-511 of human ZGPAT (NP_852150.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DPDL SSLQ AGSA CLAK HQDG LWHA ARIT DVDN GYYT VKFD SLLL REAV VEGD GILP PLRT EATE SDSD SDGT GDSS YARV VGSD AVDS GTCS SAFA GWEV HTRG IGSR LLTK MGYE FGKG LGRH AEGR VEPI HAVV LPRG KSLD QCVE TLQK QTRV GKAG TNKP PRCR GRGA RPGG RPAP RNVF DFLN EKLQ GQAP GALE AGAA PAGR RSKD MYHA SKSA KRAL SLRL FQTE EKIE RTQR DIRS IQEA LARN AGRH SVAS AQLQ EKLA GAQR QLGQ LRAQ EAGL QQEQ RKAD THKK MTEF
Gene ID:84619
Uniprot:Q8N5A5
Cellular Location:Nucleus
Calculated MW:20kDa/54kDa/55kDa/57kDa
Observed MW:57kDa
Synonyms:ZGPAT, GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP
Background:
UniProt Protein Function:Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.
UniProt Code:Q8N5A5
NCBI GenInfo Identifier:307548887
NCBI Gene ID:84619
NCBI Accession:NP_001182583.1
UniProt Secondary Accession:Q8N5A5,Q4VXN9, Q5JWI9, Q5JWJ0, Q8NC55, Q8WUV4, Q96JI0 Q96JU4, Q9H401, E1P5K1,
UniProt Related Accession:Q8N5A5
Molecular Weight:20,697 Da
NCBI Full Name:zinc finger CCCH-type with G patch domain-containing protein isoform d
NCBI Synonym Full Names:zinc finger CCCH-type and G-patch domain containing
NCBI Official Symbol:ZGPAT  
NCBI Official Synonym Symbols:ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847  
NCBI Protein Information:zinc finger CCCH-type with G patch domain-containing protein
UniProt Protein Name:Zinc finger CCCH-type with G patch domain-containing protein
UniProt Synonym Protein Names:G patch domain-containing protein 6; Zinc finger CCCH domain-containing protein 9; Zinc finger and G patch domain-containing protein
UniProt Gene Name:ZGPAT  
Anti-ZGPAT Antibody (CAB16583)Western blot analysis of extracts of rat lung, using ZGPAT antibody (CAB16583) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s.
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