Cell Biology Antibodies 14

Anti-ZDHHC7 Antibody (CAB17981)

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SKU:
CAB17981
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ZDHHC7 Antibody
Antibody SKU:CAB17981
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human ZDHHC7.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:A-431, PC-3, Mouse lung
Immunogen:Recombinant protein of human ZDHHC7.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:55625
Uniprot:Q9NXF8
Cellular Location:
Calculated MW:
Observed MW:33kDa
Anti-ZDHHC7 Antibody (CAB17981)Western blot - ZDHHC7 Rabbit pAb (CAB17981)
Synonyms:DHHC7, SERZ-B, SERZ1, ZNF370, ZDHHC7
Background:
UniProt Protein Function:ZDHHC7: Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability. Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptors. Belongs to the DHHC palmitoyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral; EC 2.3.1.225; Transferase; Membrane protein, multi-pass; Palmitoyltransferase

Chromosomal Location of Human Ortholog: 16q24.1

Cellular Component: Golgi apparatus; intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus

Molecular Function:palmitoyltransferase activity

Biological Process: peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine; protein palmitoylation

UniProt Code:Q9NXF8
NCBI GenInfo Identifier:116242853
NCBI Gene ID:55625
NCBI Accession:Q9NXF8.2
UniProt Secondary Accession:Q9NXF8,Q8WV42, Q9NVD8, D3DUM1,
UniProt Related Accession:Q9NXF8
Molecular Weight:38,917 Da
NCBI Full Name:Palmitoyltransferase ZDHHC7
NCBI Synonym Full Names:zinc finger DHHC-type containing 7
NCBI Official Symbol:ZDHHC7  
NCBI Official Synonym Symbols:DHHC7; SERZ1; SERZ-B; ZNF370  
NCBI Protein Information:palmitoyltransferase ZDHHC7
UniProt Protein Name:Palmitoyltransferase ZDHHC7
UniProt Synonym Protein Names:Zinc finger DHHC domain-containing protein 7
Protein Family:Palmitoyltransferase
UniProt Gene Name:ZDHHC7  
UniProt Entry Name:ZDHC7_HUMAN
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