Cell Biology Antibodies 17
Anti-ZCRB1 Antibody (CAB18518)
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- SKU:
- CAB18518
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ZCRB1 Antibody |
| Antibody SKU: | CAB18518 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human ZCRB1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant protein of human ZCRB1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 85437 |
| Uniprot: | Q8TBF4 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | MADP-1, MADP1, RBM36, SNRNP31, ZCCHC19, ZCRB1 |
| Background: |
| UniProt Protein Function: | ZCRB1: Up-regulated by morphine. Down-regulated at 30-36 degrees Celsius while it is up-regulated at 39 degrees Celsius. Component of the U11/U12 snRNPs that are part of the U12- type spliceosome. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 12q12 Cellular Component: nucleoplasm; U12-dependent spliceosome Molecular Function:RNA binding Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing |
| NCBI Summary: | Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8TBF4 |
| NCBI GenInfo Identifier: | 158931154 |
| NCBI Gene ID: | 85437 |
| NCBI Accession: | Q8TBF4.2 |
| UniProt Secondary Accession: | Q8TBF4,Q6PJX0, Q96TA6, |
| UniProt Related Accession: | Q8TBF4 |
| Molecular Weight: | 24,592 Da |
| NCBI Full Name: | Zinc finger CCHC-type and RNA-binding motif-containing protein 1 |
| NCBI Synonym Full Names: | zinc finger CCHC-type and RNA binding motif containing 1 |
| NCBI Official Symbol: | ZCRB1 |
| NCBI Official Synonym Symbols: | MADP1; RBM36; MADP-1; SNRNP31; ZCCHC19 |
| NCBI Protein Information: | zinc finger CCHC-type and RNA-binding motif-containing protein 1 |
| UniProt Protein Name: | Zinc finger CCHC-type and RNA-binding motif-containing protein 1 |
| UniProt Synonym Protein Names: | U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein; U11/U12-31K |
| Protein Family: | Zinc finger CCHC-type and RNA-binding motif-containing protein |
| UniProt Gene Name: | ZCRB1 |
| UniProt Entry Name: | ZCRB1_HUMAN |
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