Cell Biology Antibodies 15
Anti-ZCCHC12 Antibody (CAB18556)
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- SKU:
- CAB18556
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ZCCHC12 Antibody |
| Antibody SKU: | CAB18556 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human ZCCHC12. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant protein of human ZCCHC12. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 170261 |
| Uniprot: | Q6PEW1 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | PNMA7A, SIZN, SIZN1, ZCCHC12 |
| Background: |
| UniProt Protein Function: | ZCCHC12: Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression. Belongs to the ZCCHC12 family. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: Xq24 Cellular Component: nuclear speck Molecular Function:ligand-dependent nuclear receptor transcription coactivator activity; protein binding Biological Process: BMP signaling pathway |
| NCBI Summary: | This gene encodes a downstream effector of bone morphogenetic protein (BMP) signalling. This protein contains a zinc finger domain and functions as a transcriptional coactivator. Variation in this gene may be associated with X-linked mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] |
| UniProt Code: | Q6PEW1 |
| NCBI GenInfo Identifier: | 85718626 |
| NCBI Gene ID: | 170261 |
| NCBI Accession: | Q6PEW1.2 |
| UniProt Secondary Accession: | Q6PEW1,Q6PID5, Q8N1C1, B3KV48, |
| UniProt Related Accession: | Q6PEW1 |
| Molecular Weight: | 45,369 Da |
| NCBI Full Name: | Zinc finger CCHC domain-containing protein 12 |
| NCBI Synonym Full Names: | zinc finger CCHC-type containing 12 |
| NCBI Official Symbol: | ZCCHC12 |
| NCBI Official Synonym Symbols: | SIZN; SIZN1; PNMA7A |
| NCBI Protein Information: | zinc finger CCHC domain-containing protein 12 |
| UniProt Protein Name: | Zinc finger CCHC domain-containing protein 12 |
| UniProt Synonym Protein Names: | Smad-interacting zinc finger protein 1 |
| Protein Family: | Zinc finger CCHC domain-containing protein |
| UniProt Gene Name: | ZCCHC12 |
| UniProt Entry Name: | ZCH12_HUMAN |
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