Cell Biology Antibodies 1

Anti-ZC3H14 Antibody (CAB10364)

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SKU:
CAB10364
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ZC3H14 Antibody
Antibody SKU:CAB10364
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human ZC3H14 (NP_997545.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:MCF7, A-549, HT-1080, 293T
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human ZC3H14 (NP_997545.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MRMS SKFP SPPL PIFL PPEP VDLG SITS SSCS LNEL DNIS HLLR KISA DINE IKGM KAAI LTVE ANLF DLNV RVSK NEAK ISSL EVKM NEYS TTYE CNRQ FEDQ EEDT ESQS RTTD VKII GFLR NVEK GTQQ RQLL SRLQ IDPV MAET LQMS QAEM SELS VAQK PEKL LERC KYWP ACKN GDEC AYHH PISP CKAF PNCK FAEK CLFV HPNC KYDA KCTK PDCP FTHV SRRI PVLS PKPV APPA PPSS SQLC RYFP ACKK MECP FYHP KHCR FNTQ CTRP DCTF YHPT INVP PRHA LKWI RPQT SE
Gene ID:79882
Uniprot:Q6PJT7
Cellular Location:Cytoplasm, Nucleus speckle
Calculated MW:32-34kDa/61-66kDa/80-82kDa
Observed MW:105kDa
Synonyms:ZC3H14, MRT56, MSUT-2, NY-REN-37, SUT2, UKp68
Background:The protein encoded by this gene is a poly(A)-binding protein that can affect gene expression and poly(A) tail length. The encoded protein may influence mRNA stability, nuclear export, and translation.
UniProt Protein Function:ZC3H14: Binds the polyadenosine RNA oligonucleotides. Belongs to the ZC3H14 family. 7 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:DNA-binding; RNA-binding

Chromosomal Location of Human Ortholog: 14q31.3

Cellular Component: nuclear speck; nucleolus; nucleus

Molecular Function:protein binding; RNA binding

Disease: Mental Retardation, Autosomal Recessive 56

NCBI Summary:The protein encoded by this gene is a poly(A)-binding protein that can affect gene expression and poly(A) tail length. The encoded protein may influence mRNA stability, nuclear export, and translation. [provided by RefSeq, May 2016]
UniProt Code:Q6PJT7
NCBI GenInfo Identifier:74737935
NCBI Gene ID:79882
NCBI Accession:Q6PJT7.1
UniProt Secondary Accession:Q6PJT7,Q6MZU4, Q6PJ32, Q6PUI6, Q6PUI8, Q86TQ5, Q86TW0 A8MY46, B4DXU8, B4DZW7, B4E2H4, G3V5R4,
UniProt Related Accession:Q6PJT7
Molecular Weight:83kDa
NCBI Full Name:Zinc finger CCCH domain-containing protein 14
NCBI Synonym Full Names:zinc finger CCCH-type containing 14
NCBI Official Symbol:ZC3H14  
NCBI Official Synonym Symbols:SUT2; MRT56; UKp68; MSUT-2; NY-REN-37  
NCBI Protein Information:zinc finger CCCH domain-containing protein 14
UniProt Protein Name:Zinc finger CCCH domain-containing protein 14
UniProt Synonym Protein Names:Mammalian suppressor of tau pathology-2; MSUT-2; Renal carcinoma antigen NY-REN-37
Protein Family:Zinc finger CCCH domain-containing protein
UniProt Gene Name:ZC3H14  
Anti-ZC3H14 Antibody (CAB10364)Western blot analysis of extracts of various cell lines, using ZC3H14 antibody (CAB10364) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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