Cell Biology Antibodies 15
Anti-ZC3H12D Antibody (CAB17881)
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- SKU:
- CAB17881
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ZC3H12D Antibody |
| Antibody SKU: | CAB17881 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-230 of human ZC3H12D (NP_997243.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, THP-1, Mouse spleen, Mouse liver, Rat spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-230 of human ZC3H12D (NP_997243.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QHVL AELE RQAV LVYT PSRK VHGK RLVC YDDR YIVK VAYE QDGV IVSN DNYR DLQS ENPE WKWF IEQR LLMF SFVN DRFM P |
| Gene ID: | 340152 |
| Uniprot: | A2A288 |
| Cellular Location: | |
| Calculated MW: | 25kDa/36kDa/58kDa |
| Observed MW: | 70kDa |
 | Western blot - ZC3H12D Rabbit pAb (CAB17881) |
| Synonyms: | C6orf95, MCPIP4, TFL, dJ281H8.1, p34, ZC3H12D |
| Background: |
| UniProt Protein Function: | May regulate cell growth likely by suppressing RB1 phosphorylation (PubMed:19531561). May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages (PubMed:26134560). Serve as a tumor suppressor in certain leukemia cells (PubMed:17210687). Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation (PubMed:19531561). |
| UniProt Code: | A2A288 |
| NCBI GenInfo Identifier: | 282394049 |
| NCBI Gene ID: | 340152 |
| NCBI Accession: | NP_997243.2 |
| UniProt Secondary Accession: | A2A288,Q6ZRW2, A1L178, B2RXF4, B7WNU7, B9ZZP9, B9ZZQ0 |
| UniProt Related Accession: | A2A288 |
| Molecular Weight: | 36,199 Da |
| NCBI Full Name: | probable ribonuclease ZC3H12D |
| NCBI Synonym Full Names: | zinc finger CCCH-type containing 12D |
| NCBI Official Symbol: | ZC3H12D |
| NCBI Official Synonym Symbols: | TFL; p34; MCPIP4; C6orf95; dJ281H8.1 |
| NCBI Protein Information: | probable ribonuclease ZC3H12D |
| UniProt Protein Name: | Probable ribonuclease ZC3H12D |
| UniProt Synonym Protein Names: | MCP-induced protein 4 |
| Protein Family: | Probable ribonuclease |
| UniProt Gene Name: | ZC3H12D |
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